Twist基因与乳腺癌的发生和转移

Twist Gene and Occurence and Metastasis of Breast Cancer

乳腺癌是来源于乳腺终末导管小叶单元上皮的恶性肿瘤,多发生于中老年女性,是目前威胁女性健康常见的疾病之一。其发病率在过去的几十年中逐年增高,已跃居女性恶性肿瘤的首位。近年来的研究发现,Twist作为一种肿瘤相关基因,其在乳腺癌的发生、发展以及诊断、治疗和预后中起着重要作用。

Breast cancer,derived from the terminal duct lobular of breast,mostly occurres in elderly women and is one of common diseases that threatens the health of women.The incidence of breast cancer increased year by year in the past decades and has become the top of women cancers.In recent years,the study has found that Twist gene plays an important role in the development,diagnosis,treatment and prognosis of breast cancer as a tumor-related genes.