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胃转流术治疗2型糖尿病的机制 被引量:5

Mechanisms of gastric bypass surgery on type 2 diabetes mellitus
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摘要 2型糖尿病是一种常见的内分泌代谢性疾病,传统的治疗方法以内科为主,但不能达到终身治愈的目的.外科治疗主要是针对其并发症.近年来研究发现,胃转流术可有效治疗2型糖尿病,减少糖尿病各种并发症.目前胃转流术治疗2型糖尿病的具体作用机制仍未完全阐明,可能与胃肠道激素、脂肪细胞因子、炎性反应因子、氧化应激及胰岛素信号转导等多方面因素有关. Type 2 diabetes mellitus is a common endocrine and metabolic disease,which can not be a life-long cure by using traditional internal methods. Surgical treatment is mainly directed against its complications. Recently studies have showed gastric bypass surgery can control diabetes mellitus effectively and alleviate its complications. The mechanisms of gastric bypass surgery on type 2 diabetes mellitus are not fully understood, which are related to gut hormones, inflammatory factors, oxidative stress, insulin signaling pathway and so on.
出处 《国际内分泌代谢杂志》 2011年第3期171-173,共3页 International Journal of Endocrinology and Metabolism
关键词 2型糖尿病 胃转流术 RYGB Type 2 diabetes mellitus Gastric bypass surgery RYCB
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  • 1Zhen Li,Dong-Fei Li,Jing-Xing Dai,Yu Bai,Lin Yuan,Southern Medical University,Institute of Basic Medical Anatomy National Key Disciplines,Guangzhou 510515,Guangdong Province,China Hong-Ya Zhang,Lu-Xian Lv,Wen-Qiang Li,Second Affiliated Hospital,Xinxiang Medical College,Henan Province Key Laboratory of Biological Psychiatry,Xinxiang 453002,Henan Province,China Ou Sha,Department of Anatomy,Faculty of Medicine,Shenzhen University,Shenzhen 518060,Guangdong Province,China.Roux-en-Y gastric bypass promotes expression of PDX-1 and regeneration of β-cells in Goto-Kakizaki rats[J].World Journal of Gastroenterology,2010,16(18):2244-2251. 被引量:14

共引文献13

同被引文献51

  • 1董立国,翁剑锋,李井泉,蒲永东,吕刚,张博,刘瑞军,王晶.胃转流术治疗162例2型糖尿病的疗效观察[J].中华临床医师杂志(电子版),2012,6(16):4886-4887. 被引量:7
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  • 9Thatte S. Amniotic membrane transplantation: An option for ocularsurface disorders[J]. Oman J Ophthalmol, 2011,4(2):67-72.
  • 10邓治洲,王烈,林忆阳,王瑜.胃转流术对非肥胖型2型糖尿病的疗效观察及其对胰高血糖素样肽-1的影响[J].中国普外基础与临床杂志,2009,16(6):466-469. 被引量:38

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