胃癌空间分布与地理环境关系的研究

The Relationship between Spatial Distribution of Gastric Cancer and Geographical Environment

目的通过区域胃癌发病率空间分布特征的分析,探讨地理环境对疾病的影响。方法统计青州市2006年1月—2010年5月胃癌病例资料,利用ArcGIS、ArcView、Geoda等分析青州市胃癌发病率空间分布情况,利用SPSS分析青州市各乡镇胃癌发病率与其平均海拔的相关性。结果青州市胃癌年平均标化发病率为16.95/10万,其中男性标化发病率为24.14/10万,女性标化发病率为9.97/10万;胃癌发病率的全局自相关系数Moran’sI系数为0.533683,P<0.05;各乡镇胃癌发病率与其平均海拔的Pearson系数为0.708,在置信度(双侧)为0.01时,相关性明显。结论青州市是我国胃癌高发区,且胃癌分布存在明显空间集聚现象,高发区集中于山地丘陵地区,基岩岩性为寒武纪灰岩,发病率大体呈现由西南向东北递减的趋势。

Objective To investigate the impact of geography on disease by analyzing the status of regional spatial distribution of gastric cancer incidence rate.Methods Collecting baseline information on gastric cancer in Qingzhou from January 2006 to May 2010.ArcGIS,ArcView and Geoda were used to analyze the spatial distribution of gastric cancer incidence,and SPSS was used to analyze the correlation between gastric cancer incidence rate and the average elevation of township in Qingzhou.Results The standardized incidence rate of gastric cancer in Qingzhou was 16.95/105;24.14/105 among male and 9.97/105 among female.The Moran＇s I index of gastric cancer incidence rate was 0.533683,P0.05.The Pearson coefficient between gastric cancer incidence rate in township and average elevation of township in Qingzhou was 0.708,the confidence level of significant correlation（bilateral） was 0.01.Conclusion There is a high incidence rate of gastric cancer in Qingzhou city.The distribution of gastric cancer was obviously spatial agglomeration.High gastric cancer incidence rate centered in the hilly area,where the bedrock was cambrian limestone.There is a decreasing trend from southwest to northeast in general.