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Osterix和脂联素与骨代谢的关系 被引量:2

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摘要 正常骨代谢周期中,破骨细胞(OC)的骨吸收与成骨细胞(OB)的骨形成相互偶联,维持一种动态平衡,不断进行骨重建。当OC的骨吸收相对增强或OB的骨形成相对减弱,骨吸收大于骨形成导致骨质丢失时,将导致骨质疏松。近年来,随着细胞生物学和分子生物学研究的不断深入,细胞因子在骨代谢过程中的作用越来越受到人们的重视。细胞因子调控骨代谢过程中OB和OC的分化,增殖与功能活性,并通过自分泌、旁分泌和细胞黏附方式在骨重建中发挥重要作用。Osterix和脂联素便是新近发现的二种因子。
出处 《中国煤炭工业医学杂志》 2011年第5期779-782,共4页 Chinese Journal of Coal Industry Medicine
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参考文献29

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同被引文献53

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