摘要
采用 M T T 比色法与双抗体夹心法对38 例食管癌患者进行了手术前后 I L- 2 与 S I L-2 R 水平检测, 并以正常人作对照。结果表明:食管癌患者手术前血清 I L- 2 活性明显低于正常人,血清 S I L- 2 R 水平明显地高于正常人;术后6 个月复发者 I L- 2 与 S I L- 2 R 水平持续异常,未复发者 I L- 2 与 S I L- 2 R 水平恢复正常。观察了患者免疫功能的变化与肿瘤的发生及预后密切相关。
The dynamic changes in level of interleukin-2 (IL-2) and soluble interleukin-2 receptor (SIL-2R) were investigated before operation in carinoma of esophagus. The results showed that the IL-2 activity was significantly lower than that of normal control( P <0.01), and the SIL-2R activity was higher than that of normal control ( P <0.01). In postoperative follow-up for 6 months the IL-2 activities remanined lower and the SIL-2R values higher in the patients with recurrence, the IL-2 and IL-2R levels returned to normal in the patients without recurrence. There is correlation between immune function and the of carcinoma of esophagus.
出处
《标记免疫分析与临床》
CAS
1999年第3期141-143,共3页
Labeled Immunoassays and Clinical Medicine