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Duchenne型肌营养不良分子发病机制及基因治疗新进展 被引量：7

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摘要 Duchenne型肌营养不良（Duchenne muscular dystrophy，DMD）是最常见的肌营养不良类型，遗传方式为X染色体连锁隐性遗传。国外流行病学调查显示，发病率约为每3500至6000名活产男婴有1例发病。DMD及其良性病程表型——Becker型肌营养不良（Becker muscular dystrophy，BMD），都是由位于X染色体上的DMD基因缺陷所致，因此又统称为dystrophin病。
作者 戴毅 崔丽英
机构地区 中国医学科学院北京协和医院神经科
出处 《中华神经科杂志》 CAS CSCD 北大核心 2011年第5期350-353,共4页 Chinese Journal of Neurology
关键词 DUCHENNE型肌营养不良 分子发病机制 基因治疗 BECKER型肌营养不良 DYSTROPHIN X染色体连锁 流行病学调查 隐性遗传
分类号 R746.2 [医药卫生—神经病学与精神病学]
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参考文献35

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二级参考文献25

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共引文献9

同被引文献134

  • 1龚耀先,蔡太生.中国修订韦氏儿童智力量表[J].中国临床心理学杂志,1994,2(1):1-6. 被引量：126
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  • 3申本昌,张成,陈松林,孙筱放,李少英,姚晓黎,王淑辉,卢锡林.非缺失/重复型Duchenne肌营养不良症患者的致病点突变分析[J].中华医学遗传学杂志,2006,23(4):392-396. 被引量：16
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引证文献7

二级引证文献35

中华神经科杂志
2011年 第5期

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