国产雷帕霉素洗脱支架应用于冠状动脉分叉病变的效果评价

Effects of Drug-Eluting Stents Treatment on Coronary Bifurcation Lesions

目的评价冠状动脉分叉病变与非分叉病变支架植入术后预后是否存在差别。方法回顾性分析1877例冠心病患者,其中568例冠状动脉分叉病变患者,1309例冠状动脉非分叉病变患者。植入Excel支架,术后6、12及18个月临床随访两组主要不良心脏事件发生率的情况。结果术后6、12及18个月两组死亡(心性和非心性)、非致死性心肌梗死及主要不良心脏事件的发生率均无差别(P>0.05),6及12个月两组靶病变血运重建的发生率无差别(P>0.05),18个月两组靶病变血运重建的发生率存在差别(P<0.05)。结论 Excel支架治疗冠状动脉分叉病变具有安全性和可靠性。

Aim To evaluate if the prognosis was different between coronary bifurcation lesions and non-coronary bifurcation lesions when treated with drug-eluting stents. Methods For this retrospective study,1877 patients were enrolled.568 cases were coronary bifurcation lesions and 1309 cases were non-coronary bifurcation lesions.All of the patients were treated with Excel stents.Clinical follow-up at 6 months,12 months and 18 months were completed in all patients to evaluate the safety and efficacy. Results There were no differences on the rate of death（including cardiogenic and non-cardiogenic）,non-fatal myocardial infarction and major adverse cardiac events（MACE） at 6 months,12 months and 18 months between the two groups.There were no differences on the rate of target lesion revascularization（TLR） at 6 months and 12 months.The rate of TLR was higher at 18 months in the coronary bifurcation lesions group. Conclusion It was safe and efficient to treat coronary bifurcation lesions with Excel stent.