广东惠东地区结直肠癌的发病特点

Epidemiological and clinical characteristics of colorectal cancer in Huidong District,Guangdong Province,over the past 10 years

目的:研究近10年广东省惠东地区结直肠癌发病特点的变化.方法:回顾性分析2001-01/2010-12广东省惠东县人民医院结肠镜检出结直肠癌患者的流行病学、临床、内镜及病理资料,并对前后5年的资料进行对比分析.结果:2001-01/2010-12共行肠镜10532例,检出结直肠癌853例.2001-01/2005-12与2006-01/2010-12相比,结直肠癌的检出率由8.0%升至8.2%,中位年龄由59岁上升至65岁,直肠是最常见的发病部位(55.0%),便血是最常见的症状(56.0%).右半结肠癌的比率由15.1%升高至19.2%.病理学上,中分化腺癌占大部分(65.5%).结论:结直肠癌发病有老龄化趋势.直肠癌仍占结直肠癌的大部分,但右半结肠癌的发病率有上升趋势,应对高危人群行全结肠镜检查.

AIM：To analyze the epidemiological and clinical characteristics of colorectal cancer in Huidong District,Guangdong Province,over the past 10 years.METHODS：Data were collected from all consecutive patients receiving colonoscopy at our hospital during the past 10 years.The epidemiological data,clinical presentations,endoscopic findings,and pathohistological characteristics of patients with colorectal cancer were reviewed and analyzed retrospectively.RESULTS：A total of 10 532 patients received colonoscopy from 2001 to 2010,and of them 853 cases of colorectal cancer were identified by histological assessment.The detection rate of colorectal cancer rose from 8.0%in the first 5-year period to 8.2%in the second five-year period.The median age of patients with colorectal cancer in the second five-year period was older than that in the first five-year period（65 years vs 59 years）.The rectum is the most frequent site for colorectal cancer（55.0%）,while hematochezia is the most common symptom（56.0%）.The detection rate of right-sided colonic cancer in the second five-year period was significantly higher than that in the first five-year period（19.2%vs 15.1%,P0.05）.Histologically,adenocarcinoma was the most frequent histological subtype（65.5%）.CONCLUSION：The onset age of patients with colorectal cancer is becoming older in Huidong District,Guangdong Province.The rectum re-mains the most frequent site for colorectal cancer.The shift in site of colonic cancer toward the right has occurred.