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曲安奈德治疗视网膜静脉阻塞黄斑水肿的疗效及频域光学相干断层成像在其中的应用 被引量:4

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摘要 目的 通过频域光学相干断层成像(OCT)观察曲安奈德治疗视网膜静脉阻塞黄斑水肿的临床疗效。方法对36例视网膜静脉阻塞黄斑水肿患者应用频域OCT在曲安奈德治疗前后观察黄斑视网膜形态,术后第1天、第3天及1个月时OCT随访检查黄斑视网膜形态变化。测量以黄斑中心凹为中心,中心凹1、3、6mm直径圆形区域视网膜平均厚度及黄斑总容积。结果曲安奈德治疗前黄斑中心凹视网膜神经上皮内囊腔形成,视网膜外层弥漫性水肿,治疗后黄斑中心凹视网膜神经上皮内囊腔明显缩小或消失,黄斑中心凹形态恢复;治疗前黄斑中心凹1、3、6mm直径圆形区域视网膜平均厚度分别为(824.7±197.5)、(769.1±144.6)、(423.6±82.5)μm;黄斑总容积(14.2±3.8)mm3。治疗后1天黄斑中心凹1、3、6mmn直径圆形区域视网膜平均厚度分别为(347.3±75.8)、(426.0±103,2)、(283.04-90.6)μm;黄斑总容积(9.2±1.4)mm3。它们分别与最佳矫正视力呈直线负相关(r=-0.178、-0.216、-0.138、-0.183,均P〈0.05)。结论曲安奈德治疗视网膜静脉阻塞黄斑水肿是有效的,且安全性较理想。频域OCT能定性、定量评价曲安奈德治疗黄斑水肿的疗效。
出处 《中国医药》 2011年第6期737-739,共3页 China Medicine
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参考文献12

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二级参考文献28

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