三味辛凉归肺经中药对肺阴虚模型小鼠的影响

Effects of Three Traditional Chinese Medicine with Pungent-Flavor,Cool-Nature and Meridian Tropism in Lung on Lung-yin Deficiency Mice

目的:观察薄荷、菊花、前胡三味辛凉归肺经中药水提取物对肺阴虚模型小鼠的影响。方法:灌服甲状腺片7d,烟熏20min/d,连续8d,造肺阴虚小鼠模型。灌胃给予薄荷、菊花、前胡水提物,连续给药15d。试验期间,观察小鼠的一般行为学、体重、测量肛温、面温、抓力、自主活动。结果:薄荷、菊花、前胡水提物均可提高肺阴虚小鼠的抓力、活动次数,降低肛温;薄荷、前胡水提物降低肺阴虚小鼠面温;薄荷水提物能提高肺阴虚小鼠的体重。结论:薄荷、菊花、前胡同为辛、凉归肺经中药,可显著改善肺阴虚证之形体消瘦、面红、体倦乏力等,这为探讨"辛凉归肺经"中药的共同作用规律提供了一定参考。

Objective： To observe the effects of three TCM such as Mentha haplocalyx Brip, Chrysan the mummori folium and Peuceldanum Dunnon lung-yin deficiency mice. Methods： Lung-yin deficiency mice were established with administering thyroid tab- let for seven days and smoking for eight days,20min per day. Meanwhile,mlce were given water extracts of the three TCM by intra- gastric administration for 15 days everyday. Indexes such as general behavior, weight, diet amount, water quantity, rectal tempera- ture, face temperature, grip strength and locomotor activity were observed. Results ： The water extracts of Mentha haplocalyx Brip, Chrysanthe mummori folium and Peuceldanum Dunn could raise grip strength and locomotor activity, reduce rectal temperature. The water extracts of Mentha haplocalyx Brip and Peuceldanum Dunn could reduce face temperature. The water extracts of Mentha haplocalyx Brip could heighten weight. Conclusion; Mentha haplocalyx Brip, Chrysanthe mummori folium and Peuceldanum Dunn were TCM with pungent-flavor, cool-nature and meridian tropism in lung, which could improve the symptoms of physique ema- ciation, flushing, weary and acratia and soon. It provides an important reference for theregularity of the properties theories about pungent-flavor, cool-nature and meridian tropism in lung.