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多病因心衰患儿血NT-pro-BNP、ANP、ET水平变化及与动脉氧分压关系研究 被引量:1

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摘要 目的探讨多病因急性心力衰竭患儿血氨基末端脑利钠肽前体(NT-Pro-BNP)、心房利钠肽(ANP)、内皮素(endothelin,ET)水平变化及其与动脉氧分压的关系。方法将心衰组病例分为肺炎合并心力衰竭组(A1)20例,先天性心脏病合并肺炎心力衰竭组(A2)17例,先天性心脏病合并中重度肺动脉高压心力衰竭组(A3)13例;对照组患儿分为肺炎组(B1)21例,先天性心脏病组(B2)15例,健康儿童组(B3)16例。采用酶联免疫方法、放射免疫均相竞争法检测血NT-pro-BNP、ANP、ET水平。采用多普勒超声检测心室射血分数(LVEF)评价心功能,对先天性心脏病患儿检测肺动脉压力。结果心衰组与对照组各病例间NT-Pro-BNP、ANP、ET比较均有显著性差异,与心功能指标LVEF数值变化及血氧分压呈显著负相关。结论心衰组与对照组各病例间NT-Pro-BNP、ANP、ET比较均有显著性差异,与血氧分压呈显著负相关。中重度肺动脉高压对心衰急性期患儿血NT-pro-BNP、ANP、ET水平影响最明显。
出处 《中国医学创新》 CAS 2011年第14期22-25,共4页 Medical Innovation of China
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  • 1Mir TS,Marohn S,Laer S,et al.Plasma concentrations of N-terminal pro-brain natriurtic peptide in control children from theneonatal to adolescent period and in children with congestive heart failure.Pediatrics,2002,110:76.
  • 2KawaiK,HataK,TakaokaH,et al.Plasma brain natriuretic peptide as a noval therapetic indicator in idiopathic dilated cardiomyopathy duringβ-blocker therapy:a potential of hormone-guided treatment.Am Heart J,2001,141:925-932.
  • 3Grzybowski J,Bilinska ZT,Janas J,et al.Plasma concentrationsofN-terminal brain natriuretic peptide are raised in asymptomatic relatives of dilatec cardiomyopathy patientswith left ventricular enlargement.Heart,2002,88:191-192.
  • 4SuneelT,Downie P,Davies J,et al.PlasmaN-terminalpro BNP and cardiotrophin-1 are elevated in aortic stenosis.Eur J Heart Fail,2001,3:15-19.
  • 5Kinnunen P,VuolteenahoO,RuskoahoH,et al.Mechanisms ofatrial and brain natriuretic peptide release from ratventricularmyocardium:effect of stretching.Endocrinology,1993,132:1961-1970.
  • 6Suda K,Matsumura M,Matsumoto M.Clinical implication of plasma natriuretic peptides in childrenwith ventricular septaldefect.Pediatr Int,2003,45:249-254.
  • 7武育蓉,陈树宝,孙锟,黄美蓉,张玉奇,陈笋.现有儿科心力衰竭诊断标准及脑利钠肽对先天性心脏病合并心力衰竭的诊断价值[J].中华儿科杂志,2006,44(10):728-732. 被引量:37

二级参考文献11

  • 1马沛然,王长勇,郭雷鸣,于永慧.关于婴幼儿不同病因所致心力衰竭诊断标准的探讨[J].小儿急救医学,2004,11(4):218-220. 被引量:9
  • 2武育蓉,陈树宝,黄美蓉,张玉奇,孙锟,陈笋.氨基末端脑利钠肽前体在室间隔缺损合并心力衰竭诊断中的价值[J].中华儿科杂志,2005,43(3):161-164. 被引量:37
  • 3李树政 李家宜 宁寿葆 等.小儿心力衰竭诊断治疗方案(试行)[J].中华儿科杂志,1985,23:295-296.
  • 4Ross RD.Grading the severity of congestive heart failure in infants.Pediatr Cardiol,1992,13:72-75.
  • 5Reithmann C,Reber D,Kozlik-Feldmann R,et al.Post-receptor defect of adenylyl cyclase in severely failing myocardium fron children with congenital heart disease.Eur J Pharmacol,1997,330:79-86.
  • 6Stephanie L,Thomas S,Frederike B,et al.Carvedilol therapy in pediatric patients with congestive heart failure:a study investigating clinical and pharmacokinetic parameters.Am Heart J,2002,143:916-922.
  • 7Connolly D,Rutkowski M,Auslender M,et al.The New York university pediatric heart failure index:a new method of quantifying chronic heart failure severity in children.J Pediatr,2001,138:644-648.
  • 8Ross RD.Grading the graders of congestive heart failure in children.J Pediatr,2001,138:618-620.
  • 9Johnstone DE,Abdulla A,Arnold JM,et al.Diagnosis and management of heart failure.Can J Cardiol,1994,10:613-631.
  • 10Mir T,Stephani S,Eiselt M,et al.Plasma concentration of N-terminal pro-brain natriuretic peptide in control children from the neonatal to adolescent period and in children with congestive heart failure.Pediatrics,2002,110:e76.

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