干预措施对住院患者抗菌药物合理应用的影响

Influence of intervention measures on rational antimicrobial drug use of inpatients

目的评价干预措施对住院患者抗菌药物合理应用的影响。方法患者1027例,按有无实施干预措施分为干预组559例和非干预组468例。干预组给予相应的干预措施,非干预组不给予任何措施。观察患者平均住院天数、平均住院费、平均住院药费、抗菌药物平均使用费用、抗菌药物平均使用次数和病原学检查、药敏实验、医师使用抗菌药物通用名处方、正确给予抗菌药物的构成比。结果干预组平均住院天数、平均住院费、平均住院药费、抗菌药物平均使用费用和抗菌药物平均使用次数均明显低于非干预组,差异有统计学意义(P<0.01)。干预组病原学检查、药敏实验、药物通用名处方和正确给予抗菌药物的构成比均高于非干预组,差异有统计学意义(P<0.05和P<0.01)。结论干预措施对提高合理用药水平效果显著,体现了干预措施的有效性和可行性。

Objective Objective To evaluate influence of intervention measures on rational antimicrobial drug use ofinpatients.Methods 1027 cases were divided into intervention group of 559 and non-intervention group of 468 according to whether carrying out Intervention measures.The intervention group was carried out intervention measures and the non-intervention group did not take any measures The average hospitalization time（AHT）,average hospitalization fares,average hospitalization expense of medicine,average expense of antimicrobial drugs,the number of average usage of antimicrobial drugs,the examine of pathogeny,drug sensitive test,common name presiviption of antimicrobial drugs and constituent ratio of correct antimicrobial treatment of 2 groups were observed.Results The average hospitalization time（AHT）,average hospitalization fares,average hospitalization expense of medicine,average expense of antimicrobial drugs and the number of average usage of antimicrobial drugs in the intervention group were lower than those in the non-intervention group,the differences were statistically significant（P0.01）.The examine of pathogeny,drug sensitive test,cornmon name presiviption of antimicrobial drugs and constituent ratio of correct antimicrobial treatment in the intervention group were higher than those in the non-intervention group,the differences were statistically significant（P0.05 and P0.01）.Conclusion Intervention measures had significant effect on improving the level of rational drug use,it showed the effectiveness and feasibitily of intervention measures.