期刊文献+

慢性乙型肝炎联合抗病毒治疗专家共识 被引量:22

原文传递
导出
摘要 干扰素α(IFN—α)、核苷(酸)类似物(NUC)抗病毒单药治疗是目前慢性乙型肝炎(chronichepatitisB,CHB)的主要治疗策略,且CHB患者远期预后经抗病毒治疗后获得了显著改善。然而单药治疗应答率较低,多数患者需长期用药,停药后维持应答率较低,长期治疗耐药变异率较高,限制了CHB患者单药治疗的临床应用。
出处 《中华实验和临床感染病杂志(电子版)》 CAS 2011年第2期64-69,共6页 Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)
  • 相关文献

参考文献17

  • 1Song BC,Suh DJ,Lee HC,et al.Hepatitis B e antigen seroconversion after lamivudine therapy is not durable in patients with chronic hepatitis B in Korea. Hepatology . 2000
  • 2Papatheodoridis GV,Manesis E,Hadziyannis SJ.The long-term outcome of interferon-alpha treated and untreated patients with HBeAg-negative chronic hepatitis B. Journal of Hepatology . 2001
  • 3Fattovich G,Giustina G,Realdi G,et al.Long-term outcome of hepatitis B e antigen-positive patients with compensated cirrhosis treated with interferon alfa.European Concerted Action on Viral Hepatitis (EUROHEP). Hepatology . 1997
  • 4Carreno V,Castillo I,Molina J,et al.Long-term follow-up of hepatitis B chronic carriers who responded to in-terferontherapy. J Hepal . 1992
  • 5刘敏,易为,蔡晧东.替比夫定及干扰素相关肌炎及周围神经病[J].药物不良反应杂志,2010,12(2):130-131. 被引量:15
  • 6Sherman MRM,,Lai CL,Gadano AJIM.Long-term follow-up of entecavir treated protocoldefined nonresponders in rollover study ETV-901. Hepatology . 2007
  • 7Yang YD,Zheng L,Jie HY.De novo lamivudine and adefovir dipivoxil combination therapy for patients with decompensated cir-rhosis resulting from chronic hepatitis B. Hepatol Int . 2010
  • 8Wong VW,Wong GL,Yan KK,et al.Durability of peginterferon alfa-2b treatment at5years in patients with hepatitis B e anti-gen-positive chronic hepatitis B. Hepatology . 2010
  • 9Wong VW,Wong GL,Yan KK,et al.Durability of peginterferon alfa-2b treatment at5years in patients with hepatitis B e anti-gen-positive chronic hepatitis B. Hepatology . 2010
  • 10Di MV,Marzano A,Lampertico P,et al.Clinical outcome of HBeAg-negative chronic hepatitis B in relation to virological re-sponse to lamivudine. Hepatology . 2004

二级参考文献72

共引文献469

同被引文献179

引证文献22

二级引证文献101

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部