摘要
目的探讨血清甲胎蛋白(AFP)、a-L-岩藻糖苷酶(a-L-fucosidase,AFU)和同型半胱氨酸(homocysteine,Hcy)对原发性肝癌(primary hepatocarcinoma,PHC)的诊断价值。方法对127例原发性肝癌、80例良性肝病和50例健康人血清中AFP、AFU和Hcy进行联合检测,同时进行对比分析。结果原发性肝癌患者血清AFP、AFU和Hcy水平均明显高于良性肝病组及正常对照组,差异有统计学意义(P<0.05);AFP、AFU和Hcy联合检测的敏感性比单项检测高。结论联合检测AFP、AFU和Hcy可提高对原发性肝癌的诊断率,对早期诊断有一定的指导意义。
Objective To explore the value of diagnostic of alpha-fetoprotein（AFP）,a-L-fucosidase（AFU） and homocysteine（Hcy） in patients with primary hepatocarcinoma（PHC）.MethodsAFP,AFU and Hcy with 127 cases of primary liver cancer,80 cases of benign liver diseases and 50 healthy human were combined and analysis the difference of level.RusultsThe levels and the positive rates in serum AFP,AFU and Hcy of primary hepatocarcinoma patients were significantly higher than those of benign liver diseases patients and normal controls（P〈0.05）.The diagnostic sensitivity and accuracy of combined detection was higher than that of single assay.ConclusionTo combining the levels of AFP,AFU and Hcy has important significance to diagnose primary hepatocarcinoma.
出处
《中外医学研究》
2011年第14期53-54,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
