颌骨放射性骨坏死的研究进展

Research advances in osteoradionecrosis of the jaw

颌骨放射性骨坏死是头颈部肿瘤放疗后的常见的严重并发症,是临床医师处理时深感棘手的问题。其发展慢,病程长,发病机制至今尚未能完全明确,对其治疗措施,迄今尚无统一的标准。本文将对其定义及发生率、病因、危险因素、预防和治疗的研究进展进行综述。

Osteoradionecrosis is a common and severe complication after radiotherapy of head and neck cancer,and it is difficult for clinicians to deal with.The development of osteoradionecrosis is slow and can persist for a long time,and the pathogenesis of osteoradionecrosis is not clear.There is no uniform standard for the treatment of ORN.This review focused on the research advances in the definition,pathogenesis,risk factors,prevention and treatment of osteoradionecrosis.