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抗核抗体核型检测在混合性结缔组织病中的意义 被引量:10

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摘要 目的:探讨抗核抗体(antinuclear antibody,ANA)核型与混合性结缔组织病(mixed connective tissue disease,MCTD)临床症状的关系及ANA核型用于评估MCTD预后的意义。方法:采用间接免疫荧光法检测66例MCTD患者血清中ANA核型,并对其临床资料进行统计分析。结果:66例MCTD患者血清ANA阳性65例,阳性率98.4%;其中斑点型最常见(41例);均质型患者临床受累系统多、症状重,且转化为系统性红斑狼疮、系统性硬化症比例高于斑点型(P<0.05)。结论:ANA核型对MCTD患者病情严重性、预后评估及用药指导具有重要价值。
出处 《中华实用诊断与治疗杂志》 2011年第5期515-516,共2页 Journal of Chinese Practical Diagnosis and Therapy
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