阿托伐他汀对治疗急性脑梗死的疗效观察

目的探讨阿托他汀类药物对急性脑梗死的临床疗效。方法将2009年1月～2010年1月收治的120例急性脑梗死患者随机分为观察组和对照组,每组60例,两组采取常规治疗,其中对照组采用川穹嗪注射液治疗,观察组采用阿托伐他汀治疗,均以14d为1个疗程。比较两组患者的临床疗效以及日常生活活动能力(ADL)及神经缺损评分。结果观察组的总有效率为91.7%(55/60),对照组为80.0%(48/60),两者差异具有统计学意义(P<0.05)。且观察组的ADL、神经功能缺损评分均显著优于对照组(P<0.05)。结论在常规治疗的基础上采用阿托他汀类药物治疗急性脑梗死的疗效较好,值得临床推广应用。

Objective To observe the effect of atorvastatin on acute cerebral infarction.Methods 120 cases of acute cerebral infarction in our hospital from January 2009 to January 2010 were treated were randomly divided into two groups,60 patients in each group,based on conventional treatment,control group was given Chuan Qiong hydrochloride injection,observation group was treated with atorvastatin,14d was as a course.The clinical efficacy of the two groups,and activities of daily living（ADL） and neurological deficit score were observed.Results The total effective rate of the observation group was 91.7%（55/60）;the control group was 80.0%（48/60）,so,the difference was statistically significant,P0.05.And the observation group（ADL）neurological deficit scores were significantly better than the control group,P0.05.Conclusion Based on the conventional treatment,the use of atorvastatin in treatment of acute cerebral infarction is better,worthy of clinical application.