珠海市2406名高考学生HBsAg、ALT检测结果分析

Analysis of results of determining HBsAg and ALT in 2406 students taking college entrance examination inZhuhai City

目的：了解珠海市高考学生的乙肝表面抗原（HBsAg）和丙氨酸氨基转移酶（ALT）的异常状况，为做好高考前学生的健康指导，防治乙型肝炎工作提供依据。方法：对2406名高考学生空腹采集静脉血3ml，用速率法检测ALT，酶联免疫法（ELISA）检测HBsAg。结果：2406名高考体检者中HBsAg阳性153例，阳性率6．36％（153／2406），ALT异常者134例，异常率5．57％（134／2406）；HBsAg阳性且ALT异常者为48例，其中男性34例，女性14例，分别占男女HBsAg阳性者的34．34％，25．93％。HBsAg阴性而ALT异常者86例，占HBsAg阴性学生的3．82oA（86／2253）。在ALT升高的学生中，HBsAg阳性者的异常率高于HBsAg阴性者，男生ALT异常率明显高于女生，差异显著（P〈0．01）。结论：青少年学生群体应加强健康卫生教育，重视乙肝疫苗的强化接种，并加强高考学生的自我健康管理。

ObjectiveTo understand the positive rate of hepatitis B surface antigen （HBsAg） and abnormality state of alanine aminotransferase （ALT） in students taking university entrance examination in Zhuhai, and provide health guide of students before college entrance examination and evidence of the preventionand control of hepatitis B. Methods： 2406 college entrance examination students were collected 3ml venous blood, with the rate of detected ALT,enzyme--linked immunosorbent assay （ELISA） detection of HBsAg. Results：2406 college entrance examination results were positive in 153 cases of HBsAg, positive rate of 6.36% （153/ 2406） ,134 cases with abnormal of ALT, abnormal rate of 5. 57% （134/2406）; 48 cases were of HBsAg positive and abnormal ALT, male 34, female 14 cases,accounted for 34.34%, 25.93 %of those HBsAg-- positive men and women. 86 cases with abnormal ALT and HBsAg negative,accounted for 3.82 M （86/2253）of HBsAg--negative students. Students with the abnormal ALT, HBsag--positive persons was higher than HBsAg negative ones, boys was significantly higher than girls of abnormal ALT rate, significant difference （P 〈0.01）. Conclusion：Young group of students should be strengthened health and hygiene education,attention to hepatitis B vaccine intensive vaccination, and to strengthen the self--health management of student in college entrance examination.