桃红四物汤对AA大鼠整体及病理影响的实验研究

The Experimental Study on AA Overall and Pathological Effects in Rats with Taohongsiwu Decoction

[目的]研究桃红四物汤对试验大鼠体重、足容积及踝关节病理的影响。[方法]通过OLYMPUS显微镜观察佐剂性关节炎(AA)大鼠桃红四物汤给药组(A组)、模型组(B组)、强的松给药组(C组)及正常组(D组)滑膜、软骨、骨的病理改变。[结果]A组大鼠可见滑膜细胞轻度增生,少量炎细胞浸润。C组大鼠滑膜组织未见明显异常。A组、C组均能明显抑制AA大鼠的关节局部的早期炎症反应。[结论]桃红四物汤可改善类风湿关节炎的病情。

[Objective]To study the soup of the trial Taohongsiwu body weight,foot volume and ankle pathology.[Methods]OLYMPUS microscope adjuvant arthritis（AA） in rats treated groups Taohongsiwu soup（A group）,model group（B group）,prednisone treated group（C group） and normal group（D group） synovium,cartilage,bone pathology.[Results]A group of rats had mild proliferation of synovial cells,inflammatory cells infiltration.C group there were no obvious synovial tissue.A group,C group could significantly inhibit rat AA joint local inflammatory reaction.[Conclusion]Taohongsiwu Decoction can improve the condition of rheumatoid arthritis.