依托咪酯全凭静脉麻醉在体外循环下二尖瓣置换术中的应用

Etomidate Injection total intravenous anesthesia in Infection cycle Replacement of mitral valve Application

目的：探讨依托咪酯全凭静脉麻醉在体外循环下二尖瓣置换术中的应用效果.方法：比较体外循环下二尖瓣置换术中依托咪酯全凭静脉麻醉和丙泊酚全凭静脉麻醉的记录拔上腔（T1）、拔主动脉（T2）、拔主动脉20min后（T3）、手术结束时（T4）硝普钠泵入浓度和患者苏醒时间、ICU停留时间、术中间羟胺率等.结果：依托咪酯组在各个时间硝普钠的泵入速度均高于丙泊酚组,转机后需要使用间羟胺的例数少于丙泊酚组,苏醒时间依托咪酯组长于丙泊酚组,差异有统计学意义（P〈0.01）,转机时间与ICU停留时间二组间差异无统计学意义（P＞0.05）.结论：在体外循环下二尖瓣置换术中使用依托咪酯全凭静脉麻醉,可减少麻醉药物对心肌的抑制,维持麻醉深度,降低手术风险.

Objective ： Explore Etomidate Injection total intravenous anesthesia in Infection cycle Replacement of mitral valve Application effect. Method ： More Infection cycle Replacement of mitral valve Etomidate Injection total intravenous anesthesia and Propofo] total intravenous anesthesia Draw on record a （tl） and pulled to （t2）, pulled back to 20rain （ts）, the operation ended （h） nitric the profits into the concentration of sodium, pump and the icu time to t~.me, stop and wait. the rate of Aramine . Results with her in all the time of nitric ester that of sodium pumping and speed are higher than the group, a mooring polyphenol the use of data between Aramine polyphenol group, was less than the time to wake her at the leader in c ester polyphenol group and a statistical significance （ P〈 0.01 ） and transit time in the icu for the time difference between the two groups is no statistical significance （ P 〈0.05 ）. Conclusion ： Infection cycle Replacement of mitral valve use Etomidate Injection total intravenous anesthesia, Narcotic drugs for the suppression of the myocardium the depth of anaesthesia and operation risks.