CT引导下经皮射频消融治疗肝癌

The treatment of liver tumor by CT-guided percutaneous radiofrequency ablation

目的 评价CT引导下经皮射频消融（RFA）治疗肝癌的临床疗效.方法 对60例肝癌患者行CT引导下射频消融治疗,共73处病灶,肿瘤大小1.4～7.0 cm,平均4.2 cm,术后1个月行增强CT、甲胎蛋白（AFP）检测,以评价射频消融的治疗效果.结果 60例患者中45例病灶完全坏死,内部及边缘无明显强化;50例术前AFP升高的原发性肝癌患者39例AFP下降.并发症中2例顽固性呃逆,1例肝脓肿,3例出现表皮烫伤,2例肝内出血.结论 CT导引下射频消融治疗肝癌具有安全、微创的特点,可达到类似外科手术切除的效果.

Objective To evaluate the therapeutic effcacy with CT-guided percutaneous radiofrequency ablation（RFA）for the liver tumor.Methods 60 cases of patients with a total of 73 lesions were treated with radio-frequency ablation.The diameter of the lesions was 1.4～7.0cm.with a mean diameter of 4.2cm.The therapeutic efficacy was evaluated with enhanced CT scanning and AFP.Results 45 patients of 60 cases with lesions were full damaged,no blood flow Was found on enhanced CT scans.39 patients with significantly increased blood-AFP before treatment were decreased significantly after treatment,Complications occured in 11 patients,including refractory hiccup （n=2）,epidermal scald（n=3）,intrahepatic hemorrhage（n=2）and hepatic abscess（n=1）.Conclusion The radiofrequency ablation was simple and effective treatment of liver tumor.The effect could be similar to that of surgical resection.