期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

冠心病患者冠状动脉病变积分与血清游离脂肪酸的相关性分析 被引量：7

Correlation analysis of free fatty acids and coronary artery score in patients with coronary heart disease
原文传递
导出
摘要 目的:探讨冠状动脉病变积分(CAS)与血清游离脂肪酸(FFA)水平的关系。方法:采用ELASA法测定冠心病患者(95例)、非冠心病患者(68例)血清中游离脂肪酸水平。结果:腰围、体质指数、收缩压、舒张压、平均动脉压、脉压指数、高密度脂蛋白胆固醇、FFA均与CAS有显著相关性,多元回归分析显示CAS与FFA和高密度脂蛋白胆固醇存在显著相关性。结论:FFA与CAS有密切相关性,血清FFA可能是冠心病发生发展的良好预测指标。 Objective：To investigate whether the levels of serum free fatty acids are related to the coronary artery score（CAS）.Method：The total of 95 patients based on coronary lesions in coronary anglography,and 68 non-coronary disease patients.Serum FFA was determined by ELASA.Result：Waist circumference（WC）,body mass index（BMI）,systolic blood pressure（SBP）,diastolic blood pressure（DBP）,mean artery pressure（MAP）,pulse pressure index（PPI）,high density lipoprotein cholesterol（HDL）,FFA were significantly associated with CAS.Multiv-ariate regression analysis showed that HDL and FFA were significantly related to CAS（t=-2.971,2.155;P=0.008,0.035）.Conclusion：FFA was closely related to CAS and considered to be good predictors for the occurrence and development of coronary artery disease.
作者 刘小永 楚天舒 孙林 林志 张戈
机构地区 昆明医学院第二附属医院心内科云南省心血管病研究所冠心病基础研究室
出处 《临床心血管病杂志》 CAS CSCD 北大核心 2011年第5期364-367,共4页 Journal of Clinical Cardiology
基金 云南省科技厅基金项目资助(No:2007C0021)
关键词 冠状动脉疾病 游离脂肪酸 冠状动脉造影 Leaman's积分 coronary disease free fatty acids angiography leaman＇s score
分类号 R543.3 [医药卫生—心血管疾病]
  • 相关文献

参考文献14

  • 1VILLAREAL D T, MILLER B V 3rd, BANKS M, et al. Effect of lifestyle intervention on metabolic coronary heart disease risk factors in obese older adults[J]. AmJ ClinNutr,2006,84:1317--1323.
  • 2IKEDA T, IWATA K, OCHI H. Effect of insulin, proinsulin, and amylin on rennin release from per- fused rat kidney[J]. Metabolism, 2001,50 ;763- 766.
  • 3无.慢性稳定性心绞痛诊断与治疗指南[J].中华心血管病杂志,2007,35(3):195-206. 被引量：2090
  • 4柯元南,陈纪林.不稳定性心绞痛和非ST段抬高心肌梗死诊断与治疗指南[J].中华心血管病杂志,2007,35(4):295-304. 被引量：2157
  • 5高润霖.急性心肌梗死诊断和治疗指南[J].中华心血管病杂志,2001,29(12):710-725. 被引量：5018
  • 6BERNARD J G, EUGENE B, JOHN D R. Chronic coronary artery disease [M]// BRAUNWALD E, eds. Heart disease:A textbook of cardiovascular medicine. 5th ed. Philadelphia: W. B. Saunders, 1997:1289-1365.
  • 7LEAMAN D M, BROWER R W, MEESTER G T, et at. Coronary artery atherosc lerosis., severity of the disease, severity of angina pectoris and comp-romised left ventricular funcion[J]. Circulation, 1981,63 : 285 --292.
  • 8VII.I.AREAI. D T, MILLER B V, BANKS M. Effectof lifestyle intervention on metabolic coronary heart disease risk factors in obese older adults [J].Am J Clin Nutr,2006,84:1317-1323.
  • 9ZHOU Z, LIU Y, MIAOA D, et al. Protoeatechuic aldehyde suppresses TNF-alpha-induced ICAM-1 and VCAM-1 expression in human umbilical vein endothelial cells[J]. Eur J Pharmacol,2005,513:1-8.
  • 10曽小莉,郭晶,袁慧.游离脂肪酸和磷脂与冠状动脉病变的关系研究[J].临床检验杂志,2007,25(5):376-377. 被引量：6

二级参考文献75

  • 1李小鹰.阿司匹林在动脉硬化性心血管疾病中的临床应用:中国专家共识(2005)[J].中华心血管病杂志,2006,34(3):281-284. 被引量：194
  • 2Lawson WE, Hui JC, Lang G. Treatment benefit in the enhanced external counterpulsation consortium. Cardiology, 2000,94 ( 1 ) :31-35.
  • 3Ryden L, Standl E, Bartnic M, et al. Guideline on diabetes, prediabetes and cardiovascular disease:executive summary. The Task Force on Diabetes and Cardiovascular Disease of European Society of Cardiology (ESC) and of the Euopean Association for the Study of Diabetes(EASD). Eur Heart J,2007,28( 1 ) :88-136.
  • 4Crawford MH, Bernstein SJ, Deedwania PC, et al. ACC/AHA Guidelines for Ambulatory Electrocardiography. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines ( Committee to Revise the Guidelines for Ambulatory Electrocardiography). Developed in collaboration with the North American Society for Pacing and Electrophysiology.J Am Coll Cardiol,1999,34(3) :912-948.
  • 5Campeau L. Letter: Grading of angina pectoris. Circulation 1976 :54(3) :522-523.
  • 6O'Rourke RA, Brundage BH, Froelicher VF, et al. American College of Cardiology/American Heart Association Expert Consensus Document on electron-beam computed tomography for the diagnosis and prognosis of coronary artery disease. J Am Coll Cardiol, 2000,36(1) :326-340.
  • 7Gibbons Pal, Abrams J, Chatterjee K, et al. ACC/AHA 2002 guideline update for the management of patients with chronic stable angina-sunanary article: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (Committee on the Management of Patients With Chronic Stable Angina). J Am Coll Cardiol, 2003,41 ( 1 ) : 159-168.
  • 8Malik S, Wong ND, Franklin SS, et al. Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults. Circulation, 2004,110(10) :1245-1250.
  • 9Girman CJ, Rhodes T, Mercuri M,et al. The metabolic syndrome and risk of major coronary events in the Scandinavian Simvastatin Survival Study (4S) and the Air Force/Texas Coronary Atherescleresis Prevention Study (AFCAPS/TexCAPS). Am J Cardiol,2004,93 ( 2 ) : 136-141.
  • 10Kjekshus JK, Maroko PB, Sobel BE. Distribution of myocardial injury and its relation to epicardial ST-segment changes after coronary artery occlusion in the dog. Cardiovasc Res,1972,6(5) :490-499.

共引文献8889

同被引文献69

引证文献7

二级引证文献67

临床心血管病杂志
2011年 第5期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部