二维斑点追踪成像技术评价冠心病患者左室长轴应变

Evaluation of Longitudinal Strain of Left Ventricle in Patients with Coronary Artery Disease

目的:运用二维斑点追踪成像(STI)技术评价静息状态下冠心病患者左室长轴应变,探讨该参数在评判冠心病不同危险程度中的价值。方法:疑诊冠心病患者51例,根据冠状动脉造影结果将患者分为冠心病高危组、冠心病低危组及对照组,获得清晰的心尖四腔、三腔、两腔图像后存盘供脱机分析。测量参数:左室18节段平均长轴应变(MLS),基底水平、中段水平及心尖水平6个室壁节段平均长轴应变(PLS)。结果:与对照组比较,冠心病高危组基底水平、中段水平、心尖水平PLS及MLS均显著减低,冠心病低危组基底水平、中段水平PLS及MLS均显著减低,而心尖水平PLS较对照组无变化;与冠心病低危组比较,冠心病高危组基底水平、中段水平PLS及MLS显著减低。结论:STI能无创测量左室长轴应变的微小变化,为静息状态下准确评价不同危险程度冠心病患者心脏长轴收缩功能提供了新方法。

Objective： To evaluate the long axis strain of left ventricle in patients with coronary artery disease（CAD） in baseline.Methods： According the results of selective coronarography,51 cases with suspected CAD were divided into three groups： group of high risk CAD,group of low risk CAD,and control group.Apical views of 4-,3-,or 2-chamber were acquired in all patients.The data were measured included mean longitudinal strain（MLS）,peak longitudinal strain（PLS） at basal,middle and apical levels respetively.Results： Compared with the controls.PLS at basal,middle and apical levels of group of CAD high risk decreased significantly;PLS at basal and middle levels of group of low risk CAD decreased significantly,but did not change at apical level.Compared with that respectively in group of CAD low risk,PLS and MLS at all the three levels decreased significantly in high risk CAD group.Conclusion： STI can non-invasively detect the subtle changes in longitudinal strain of left ventricular and is a novel and precise method for evaluating the longitudinal function of patients with CAD.