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烟曲霉胶霉毒素的研究进展 被引量:6

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摘要 胶霉毒素作为烟曲霉产生的真菌毒素之一,对哺乳动物细胞具有免疫抑制及促凋亡作用。其通过抑制NAPDH氧化酶活性进而抑制粒细胞抗微生物作用。在侵袭性曲霉病动物模型和临床确诊患者血清中均可检测到胶霉毒素,预示其可作为曲霉病诊断指标。本文将从胶霉毒素合成的操控基因组成、分布、致病性及临床检测前景予以综述。
出处 《中国真菌学杂志》 2011年第2期118-121,共4页 Chinese Journal of Mycology
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