复发性脑梗死的危险因素分析

Risk factors of recurrent cerebral infarction

目的探讨复发性脑梗死的危险因素。方法对50例复发性脑梗死患者及51例初发性脑梗死患者的危险因素中12个因素进行对比分析,并用多元Logistic回归分析各因素与复发性脑梗死的关系,用多元相关分析各危险因素间的相关性。结果复发性脑梗死组的吸烟史、糖尿病史、高血压病史、高脂血症史、TIA史、房颤史、Hhcy的比例明显高于初发性脑梗死组(P均<0.05)。多元Logistic回归分析显示,糖尿病史(P=0.030)、TIA史(P=0.043)、房颤病史(P=0.016)和Hhcy(P=0.042)是复发性脑梗死的主要危险因素。多元相关分析显示该5项因素间没有相关性。结论糖尿病史、TIA史、房颤病史和Hhcy是复发性脑梗死的独立危险因素。

Objective To explore the risk factors of recurrent cerebral infarction. Methods 50 patients with recurrent cerebral infarction were analyzed retrospectively and 51 patients with first cerebral infarction were enrolled as the control group. A total of 12 factors were analyzed with chisquare test or t test,and their affected degree was determined with mutiple logistic regression analysis,and all risk factors were analyzed with multi-variable correlation analysis. Results The proportions of smoking history, diabetes history, hypertensive disease history, Hyperlipidemia history, TIA history, fibrillation atrial history and hyperhomocysteinemia on admission were all significantly higher in the recurrent group （P〈0. 05）. The multivariable logistic regression analysis showed that the important risk factors of early exacerbation of ischemic stroke were diabetes history （P = 0. 030）, TIA history （P = 0. 043） ,fibrillation atrial history （P = 0. 016） and hyperhomocysteinemia （P = 0. 042）. multi-variable correlation analysis showed that these 5 factors were not correlative between each other. Conclusions The independent risk factors of recurrent cerebral infarction are the diabetes history, TIA histo- ry, fibrillation atrial history and hyperhomocysteinemia.