甲状腺乳头状癌的多普勒超声特征与淋巴结转移的关系

Correlation of Doppler sonographic characteristics with lymph node metastasis in papillary thyroid carcinoma

目的:探讨甲状腺乳头状癌(papillary thyroid carcinoma,PTC)的多普勒超声特征及其与颈部淋巴结转移情况间的关系。方法:采用彩色多普勒超声评估162例患者的169个PTC结节;另采用脉冲多普勒超声评估同一批80例患者的80个PTC结节。彩色多普勒超声主要评估癌结节的血管模式和血供程度。脉冲多普勒主要分析血流流速曲线的参数,包括收缩期峰值血流速度(peak systolic velocity,PSV)、搏动指数(pulsatility index,PI)、阻力指数(resistance index,RI)、PSV差值、PI差值和RI差值。将上述超声特征与颈部淋巴结转移作单因素分析,研究各超声特征与颈部淋巴结转移情况间的关系。结果:多普勒超声上,与颈部淋巴结转移有关的超声特征主要有癌结节的血供程度及RI差值。结论:特定的多普勒超声特征可在一定程度上提示PTC发生颈部淋巴结转移的可能性。

Objective To investigate the Doppler sonographic characteristics and its correlation with cervical lymph node metastasis in papillary thyroid carcinoma（PTC）.Methods Color Doppler sonography was performed in 162 PTC patients with 169 PTC nodules,and pulse Doppler sonography was performed for 80 PTC nodules in 80 of the patients.Color Doppler sonography was used mainly for assessing the vascular pattern and level of blood supply,and pulse Doppler sonography was mainly for analyzing the parameters of blood flow velocity curve including peak systolic velocity（PSV）,pulsatility index（PI）,resistance index（RI）,and discrepancies of PSV,PI and RI.Single variable analysis was performed to evaluate the correlation of above-mentioned sonographic characteristics with cervical lymph node metastasis.Results Of Doppler sonographic characteristics,level of blood supply and discrepancy of RI of PTC nodule had correlation with cervical lymph node metastasis.Conclusions Some specific Doppler sonographic characteristics can in some extent predict the development of cervical lymph node metastasis.