调节性树突细胞与免疫负向调控
摘要
树突状细胞（dendritic cells,DCs）是具有最强抗原提呈功能的专职抗原提呈细胞（antigen-presentingcell,APC）,由于它能高水平表达MHCⅡ类分子且高效率提呈抗原,有强大的激活CD8＋、CTL及CD4＋T辅助细胞的能力,
出处
《泰山医学院学报》
CAS
2011年第3期228-232,共5页
Journal of Taishan Medical College
基金
山东省自然科学基金项目(2008ZR09517)
参考文献21
-
1LiH,Zhang GX,Chen Y,et al.CD11c+CD11b+ dendritic cells play an important role in intravenous tolerance and the suppression of experimental autoimmune encephalomyelitis[J].J Immuno,2008,181 (4):2483-2493.
-
2Sato K,Yamashita N,Baba M,et al.Regulatory dendritic cells protectmice from murine acute graft-versus-hostdisease and leukemia relapse[J].Imminity,2003,18(3):367-379.
-
3Zhang M,Tang H,Guo Z,et al.Splenic stroma drivesmature dendritic cells to differentiate into regulatory dendritic cells[J].Natlm-munol,2004,5(11):1124-1133.
-
4Xia S,Guo ZH,Xu XF,et al.Hepatic microenvironroent programs hematopoietic progenitor differentiation into regulatory dendritic cells maintaining liver tolerance[J].Blood,2008,112 (8):3175 -318.
-
5Wong K,Rodriguez A.Plasmodium infection and endotoxic shock induce the expansion of regulatory dendritic cells[J].J Immunol,2008,180(2):716-726.
-
6Hackstein H,Thomson AW.Dendritic cells:energing pharmaco-logical targets of immunosuppressive drugs[J].Nat Rev Immuno,2004,4(1):24-34.
-
7Chang CC,Ciubotariu R,Manavalan JS.Tolerization of dendritic cells byT(S) cells the crucial role of inhibitory receptors ILT3 and ILT4[J].Nat Immunol,2002,3(3):237-243.
-
8Xiao BG,WuXC,Yang JS.Therapeutic potential of IFN-γ modified dendritic cells in acute and chronic experimental allergic en-cephalomyelitis[J].Int Immunol,2004,16(2):13-22.
-
9Bonham CA,Peng L,Liang X,et al.Marked prolongation of cardiac allograft survival by dendritic cells genetically engineered with NFkappa B oligodeoxyribonucleotide decoys and adenoviral vectors encodingCTLA-Ig[J].J Immunol,2002,169(6):3382-3391.
-
10Chorny A,Gonzalez-Rey E,Fernandez-Martin A,et al.Vasoac-tive intestinal peptide induces regulatory dendritic cells that prevent acute graft-versus-host disease while maintaining the raft-ver-sus-tumor response[J].Blood,2006,107(9):3787-3794.
-
1厉倩,曹雪涛（审校者）.树突状细胞与免疫负向调控[J].国际免疫学杂志,2006,29(1):48-51. 被引量：9
-
2刘苍春,黄一虹,冯洒然,谷红红,曾令宇,李德鹏,徐开林.CD11c^(low)CD45RB^(high)调节性树突状细胞的诱导培养及鉴定[J].中国组织工程研究,2012,16(53):9987-9993.
