摘要
目的探讨使用尿激酶院前急救与住院溶栓治疗急性心肌梗死(AMI)的不同疗效,并探讨院外溶栓治疗AMI的可行性。方法选择本院救治的90例AMI患者,先期确诊行院前溶栓组44例,入院后溶栓组46例。院外救治组诊断AMI后立即给尿激酶150万U静脉点滴,同期住院后确诊的46例按上述方法立即溶栓。结果确诊后溶栓时间:院外急救组为(1.40±0.35)h,院内溶栓组为(2.51±1.55)h。治疗后冠状动脉总再通率:院前溶栓组80.9%(33/42),2例死亡;住院溶栓组70.5%(31/44),2例死亡(P<0.05)。结论入院前早期溶栓治疗AMI患者可以增加冠状动脉的再通率,安全可行,值得提倡。
Objective:To investigate the effect of thrombolytic therapy by Urokinase in acute myocardial infarction on omparative first-aid and hospitalized,and to explore the feasibility,safety of the pre-hospital thrombolytic therapy in patients with AMI.Methods:Ninety cases of AMI patients were divided into groups of 44 cases of pre-hospital thrombolysis and the hospital thrombolytic group of 46 cases after admission.The first-aid treatment received intravenous Urokinase 1.5 mg immediately after the diagnosis,and 46 cases of hospitalized patients had thrombolytic therapy immediately in hospital by the above method.Results:After diagnosis of AMI,thrombolytic time was(1.40±0.35) hours in the first-aid thrombolysis group,and(2.51±1.55) hours in the hospital thrombolysis group.The total coronary artery patency rate was 80.9% in the pre-hospital thrombolysis group(33/42),and there were 2 deaths;the hospital thrombolysis group was 70.5%(31/44),and there were 2 deaths(P0.05).Conclusion:The pre-hospital thrombolysis in AMI patients takes significantly shorter time to start thrombolysis,and coronary artery patency rate increases,so it is feasible and safe.
出处
《泰山医学院学报》
CAS
2011年第2期113-115,共3页
Journal of Taishan Medical College
关键词
尿激酶
院前救治
溶栓疗法
急性心肌梗死
Urokinase
first-aid treatment
thrombolytic therapy
acute myocardial infarction