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树突状细胞与丙型病毒性肝炎

Dendritic cells and hepatitis C
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摘要 树突状细胞(DC)是目前已知体内功能最强的抗原递呈细胞,在丙型肝炎病毒(HCV)感染的患者,DC功能减弱可促进病毒的持续感染,造成疾病的慢性化。目前DC成为HCV疫苗的研究重点,可能成为治疗慢性丙型肝炎(CHC)的有效免疫学方法,本文就DC与丙型肝炎的关系及其在治疗中的应用前景作一综述。 Dendritic cells（DCs） are currently known as the most powerful antigen-presenting cells.In patients with HCV infection,dysfunction of DCs can cause persistent viral infection leading to chronicity of the disease.DCs have become an important research focus for HCV vaccination,and it will be an effective immunology method for the treatment of viral hepatitis C.In this review,we summarized the relationship of DCs in viral hepatitis C and its perspective in the role of treatment.
作者 魏峰 李俊卿 周俊英
机构地区 河北医科大学第三医院感染科
出处 《临床肝胆病杂志》 CAS 2011年第5期549-552,共4页 Journal of Clinical Hepatology
关键词 肝炎 丙型 树突状细胞 hepatitis C dendritic cells
分类号 R392 [医药卫生—免疫学]
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参考文献21

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二级参考文献10

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临床肝胆病杂志
2011年 第5期

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