摘要
AIM:To investigate the preoperative factors that can predict neoplastic polypoid lesions of the gallbladder(PLGs) as well as malignant PLGs.METHODS:A retrospective analysis was conducted on the 210 consecutively enrolled patients who underwent cholecystectomy due to a PLG larger than 10 mm,as was determined by preoperative trans-abdominal ultrasonography or endoscopic ultrasonography.We ana-lyzed the medical,laboratory,radiologic data and the pathologic results.RESULTS:In 210 cases,146 had non-neoplastic polyps(69.5%) and 64 cases were neoplastic polyps(30.5%).An older age(≥ 65 years),the presence of diabetes mellitus(DM) and the size of polyp(≥ 15 mm) were revealed to be independent predictive variables for neoplastic polyps with odd ratios(OR) of 2.27(P = 0.044),2.64(P = 0.021) and 4.94(P < 0.01),respectively.Among the neoplastic PLGs,an older age(≥ 65 years),the presence of DM and polyp size(≥ 15 mm) were associated with malignancy with ORs of 4.97(P = 0.005),6.13(P = 0.001) and 20.55(P < 0.001),respectively.CONCLUSION:Among patients with PLGs larger than 10 mm in size,higher risk groups such as elderly patients more than 65 years old,those with DM or a large polyp size(≥ 15 mm) should be managed by cholecystectomy.
AIM：To investigate the preoperative factors that can predict neoplastic polypoid lesions of the gallbladder（PLGs） as well as malignant PLGs.METHODS：A retrospective analysis was conducted on the 210 consecutively enrolled patients who underwent cholecystectomy due to a PLG larger than 10 mm,as was determined by preoperative trans-abdominal ultrasonography or endoscopic ultrasonography.We ana-lyzed the medical,laboratory,radiologic data and the pathologic results.RESULTS：In 210 cases,146 had non-neoplastic polyps（69.5%） and 64 cases were neoplastic polyps（30.5%）.An older age（≥ 65 years）,the presence of diabetes mellitus（DM） and the size of polyp（≥ 15 mm） were revealed to be independent predictive variables for neoplastic polyps with odd ratios（OR） of 2.27（P = 0.044）,2.64（P = 0.021） and 4.94（P 0.01）,respectively.Among the neoplastic PLGs,an older age（≥ 65 years）,the presence of DM and polyp size（≥ 15 mm） were associated with malignancy with ORs of 4.97（P = 0.005）,6.13（P = 0.001） and 20.55（P 0.001）,respectively.CONCLUSION：Among patients with PLGs larger than 10 mm in size,higher risk groups such as elderly patients more than 65 years old,those with DM or a large polyp size（≥ 15 mm） should be managed by cholecystectomy.
关键词
胆囊
息肉
肿瘤
胆囊炎
糖尿病
外科手术前的因素
Gallbladder
Polyp
Neoplastic
Cholecystectomy
Diabetes
Pre-operative factors
