多重感染性腹膜炎的分类及防治

Classification,prevention and treatment of polymicrobial peritonitis

多数腹膜透析患者的腹膜炎为单一病原微生物感染,由多种病原微生物感染者少见,其发病机制不明,很可能由腹部疾病所致,并可能与早期使用广谱抗生素导致的肠道菌群失调相关。真菌和细菌混合性感染的腹膜炎预后较差、治愈率低、复发率高,早期诊断、尽早针对性治疗尤为重要。

Peritoneal dialysis （PD） -associated peritonitis was usually caused from single-organism. Polymicrobial peritonitis was associated with a significantly lower frequency. The pathogenesis remains unclear. It was likely attributed to abdominal diseases, and may be attributed to the enteric dysbacteriosis caused by early usage of wide-spectrum antibiotics. Peritonitis mixed with fungi and bacteria has bad prognosis, low cure rate and high recurrence rate. Early diagnosis and pertinent therapy are particularly important.