复方守宫散联合化疗治疗晚期胃肠癌临床研究

The Chincal Efficacy of Chemotherapy Combined with Fufang Shougong San inTherapy of Advanced Gasfric/colon Cancers

目的观察中药复方守宫散联合化疗与单用化疗治疗晚期胃肠癌的临床疗效。方法将59例晚期胃肠癌住院患者随即分为治疗组(复方守宫散联合化疗)30例和对照组(单纯化疗)29例分别给予相应治疗。观察两组近期临床疗效、生活质量、毒副作用等。结果治疗组近期有效率为56.7%(17/30),对照组51.7%(15/29),两组之间差异无统计学意义(P>0.05)。治疗组较对照组生活质量(KPS评分)明显提高(P<0.05)治疗组化疗毒副反应与对照组比较有统计学意义(P<0.05)。结论复方守宫散联合化疗治疗晚期胃肠癌,能够改善患者生活质量,降低化疗期间的毒副作用,可使患者病情进展延缓。

Objective To explore the clinical efficacy of Fufang Shougong San on combined with chemocherapy for advanced gasfric/colon cancers.Methods Total of 59 cases of gasfric/colon cancer patients 30cases in the therapy group treated by chemocherapy and Fufang Shougong San,the control group 29 patients treated by chemocherapy.Reaults The response rates in the theated group and control group were 56.7% and 51.7%.respectively,with no significant difference,P0.05.Tere were significant difference in karnosfsky score（KPS）.the treated group and control group,P0.05.Conclusion Fufang Shougong San combination chemotherapy in advanced gastrointestinal cancer,can improve the quality of life of patients and reduce side effects during chemotherapy,can delay disease progression in patients.