绝经前全子宫切除对保留卵巢的影响

目的:探讨绝经前全子宫切除对保留卵巢的影响情况,以利于临床采取治疗措施。方法:选择2010年1月～8月住院尚未闭经患者57例,均行全子宫切除,同时选择正常月经妇女50例作为对照组,对照组和患者组在术前和术后6个月进行血清中的促卵泡生成素(FSH)、促黄体生成素(LH)、垂体泌乳素(PRL)、雌二醇(E2)进行检测。结果:子宫切除组术前和术后与对照组比较PRL、E2比较相对偏低,FSH、LH水平是比对照组升高,子宫切除组术前与对照组促卵泡生成素(FSH)、促黄体生成素(LH)、垂体泌乳素(PRL)、雌二醇(E2)比较,差异无显著性,P>0.05,术后结果与术前和对照组比较差异有显著性,P<0.05。结论:绝经前妇女子宫切除后,卵巢功能减退,甚至衰竭,使绝经前妇女出现更年期症状。

Objective： To retain discussion of premenopansal hysterectomy with ovarian effect, so as to facilitate the clinical treatment measures. Methods： Selection of our hospital between 2010 and January - August has not yet been 57 cases of amenorrhea in hospital, total hysterectomy, select the normal menstrual 50 cases of women as a control group, the control group and patient groups in preoperative and postoperative serum follicle stimulating angiopoietin 6 months FSH, and luteinizing hormone LH and pituitary prolactin PRL and estradiol E2 for testing. Result ： Hysterectomy group of preoperative and postoperative controlled comparison of PRL, E2 is relatively low, FSH and LH level is higher than the control group. the hysterectomy group before operation and control of follicle stimulating angiopoietin FSH, and luteinizing hormone LH and pituitary prolactin PRL and estradiol E2 , no sig- nificant difference, P 〉 0. 05, preoperative and postoperative results and control groups are significant differences, P 〈 0. 05. Conclusion ： premenopausal women with endometrial resection and ovarian dysfunction and failure to make premenopausal women men- opause symptoms appeared.