摘要
The effects of noise and a periodic signal on a synthetic gene network have been investigated. By tuning the distance of a parameter from the Hopf bifurcation point, both implicit internal signal stochastic resonance and explicit internal signal stochastic resonance can be induced by noise. Furthermore, a switch process can also be elicited. When a periodic signal is coupled to the gene network, two interesting phenomena occur with the modulation of the frequency of the signal: the effect of noise amplifying cellular signal can be inhibited or even destroyed, and "locked" coherence resonance occurs.
The effects of noise and a periodic signal on a synthetic gene network have been investigated. By tuning the distance of a parameter from the Hopf bifurcation point, both implicit internal signal stochastic resonance and explicit internal signal stochastic resonance can be induced by noise. Furthermore, a switch process can also be elicited. When a periodic signal is coupled to the gene network, two interesting phenomena occur with the modulation of the frequency of the signal： the effect of noise amplifying cellular signal can be inhibited or even destroyed, and ＂locked＂ coherence resonance occurs.
基金
supported by the National Natural Science Foundation of China (20905009 and 21003010)
the Logistics Management & Engineering Platform of Beijing Area Logistics System & Technology Major Laboratory, and Excellent Young Scholars Research Fund of Beijing Institute of Technology (2009 Y1017)
