孕激素拮抗剂对早期胚胎主要器官影响的形态学观察

MORPHOLOGICAL OBSERVATION FOR MAIN ORGANS OF EMBRYO EFFECTED BY PROGESTERONE ANTAGONIST

目的：为了进一步了解孕激素拮抗剂米非司酮对早期胚胎主要器官发育有无影响。方法：对停经４０～４９ｄ的孕妇，进行米非司酮药流，收集排出的孕囊，用质量浓度为１０％的福尔马林液固定，常规切片、染色。光镜观察。结果：观察胚胎心脏、肝脏、肾脏及绒毛结构，与对照组同期标本相比较无差异。结论：米非司酮对早期胚胎主要器官结构无明显影响。

Objective:Effect of progesterone antagonist(mifepristones)on main organs of embryos was studied Methods:Embryonic samples were obtained from women who took mifepristons after amenorrhoea for about40 49 days Samples were fixed in 10% formalin solution,Following the regular procession for section and staining,the structures of embryos were observed under the light microscope Result:There is no difference between the research and control groups in morphological stuctrues Conclusion:There is no obvious effect of mifepristone on the structures of main organs in embryos