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老年人术后认知功能障碍的影响因素和预防 被引量:1

Impact Facts and Prophylaxis of Postoperative Cognitive Dysfunction in the Elderly
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摘要 人口老龄化问题日趋严重,老龄社会已悄然到来,老年人手术,术前、术中、术后都有其独特性,如何避免或者减少手术后并发症的发生,尤其是预防严重并发症的发生意义重大。笔者从老年人生理改变,老年人术后认知功能障碍(postoperative cognitive disorder,POCD)的影响因素以及手术前、手术中(麻醉期)、手术恢复期等阶段说明如何预防POCD的发生。对临床麻醉工作有指导意义,避免POCD的发生对家庭,对社会都有积极的意义。 The problems associated with an aging population are intensifying. An aged population has quietly arrived along with surgeries on them that have preoperative, intra--operative and postoperative issues. Each has its individual concerns such as how to avoid or reduce the incidence of complications after surgery, especially to prevent serious complications. The elderly have physiological changes and special attention needs to be paid before the operation, during surgery (anesthesia phase), and during surgical convalescence. Of particular concern is preventing the occurrence of postoperative cognitive dysfunction (POCD). For clinical anesthesia work, it is significant to avoid the occurrence of POCD for the patient, the family, and society. Avoiding POCD has a positive impact.
机构地区 大连市解放军
出处 《医学与哲学(B)》 2011年第5期50-52,共3页 Medicine & Philosophy(B)
关键词 老年 术后认知功能障碍 麻醉 elderly, postoperative cognitive disorder, anesthesia
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参考文献17

  • 1Shackelford D P, Lalikos J F. Estrogen replacement theraty and the surgeon[J].Am J surg,2000,179:333-336.
  • 2Dodds C, Allison J. Postoperative cognitive deficit in the elderly slitgal patient[J]. Br J Anaesth,1998,81(3) :449-462.
  • 3Moller J T, Cluitmans P, Rasmussen L S, et al. Longterm postop erative cognitive dysfunction in the elderly ISPOCD1 study. IS- POCD investigators. International Study of Postoperative Cognitive Dysfunction[J]. Lancet, 1998,351:857-861.
  • 4Priebe H. The aged cardiovascular risk patient[J]. Br J Anaesth, 2000,85:763-778.
  • 5Smail S. Age related memory decline : Current concepts and future directions[J]. Arch Neurol , 2001, 58 ~ 360- 364.
  • 6Peters A. structural changes that occurduring normal aging of pri- mate cerebral hemispheres[J]. Neurosci Biobehav Rev, 2002, 26: 733-741.
  • 7Epstein M. Aging and the kidney[J]. J Am soc Nephrol, 1996,7: 1106-1122.
  • 8Stemmelin J, Cassel J C, Will B, et al. Sensitivity to cholin- ergicdrug treatment of aged rats with avirable degrees of spatial memoryimpairment [J]. Behav Brain Res, 1999,98(1) :53-66.
  • 9Hunter K F, Cyr D. Pharmacotherapeutics in Older Adults[J]. JWound Ostomy Continence Nurs, 2006,33 (6):630- 638.
  • 10孟凡军,李燕,李刚,张炳熙.丙泊酚对大鼠学习和记忆功能的影响[J].临床麻醉学杂志,2005,21(6):408-410. 被引量:11

二级参考文献11

  • 1Mecca RS,陈辉,林建东.麻醉苏醒恢复期的并发症[J].国外医学(麻醉学与复苏分册),1993,14(1):50-53. 被引量:18
  • 2刘仁玉,吴安生.术后躁动[J].国外医学(麻醉学与复苏分册),1995,16(1):35-37. 被引量:60
  • 3N'Kaoua B, Veron AL, Lespinet VC,et al. Time course of cognitive recovery after propofol anaesthesia: a level of processing approach. J Clin Exp Neuropsychol, 2002,24: 713-719.
  • 4Sanou J, Goodall G, Capuron L, et al. Cognitive sequelae of propofol anaesthesia. Neuroreport. 1996, 7: 1130-1132.
  • 5Zhan H, Tada T, Nakazato F, et al. Spatial learning transiently disturbed by intraventricular administration of ouabain. Neurol Res, 2004,26: 35-40.
  • 6Lynch MA. Long-term potentiation and memory. Physiol Rev,2004,84: 87-136.
  • 7Craver CF . The making of a memory mechanism. J Hist Biol,2003,36: 153-195.
  • 8Easton A, Parker A. A cholinergic explanation of dense amnesia.Cortex, 2003,39: 813-826.
  • 9Bon CL,Garthwaite J. On the role of nitric oxide in hippocampal long-term potentiation. J Neurosci, 2003, 23:1941-1948.
  • 10Wei H, Xiong W, Yang S, et al. Propofol facilitates the development of long-term depression (LTD) and impairs the maintenance of long-term potentiation (LTP) in the CA1 region of the hippocampus of anesthetized rats. Neurosci Lett, 2002,324 : 181-184.

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