男性尿道癌3例报告

Urethral carcinoma of male:a report of 3 cases

目的探讨男性尿道癌临床特点和诊治措施。方法总结本院2000~2008年诊治的3例男性尿道癌的临床资料,并结合文献讨论。结果男性尿道鳞癌2例,移行细胞癌1例。1例尿道鳞癌行膀胱、前列腺、精囊、阴茎全切和盆腔淋巴结清扫术及回肠膀胱术,术后2年死于心肌梗死。1例尿道鳞癌行膀胱、前列腺、精囊、阴茎全切、耻骨部分切除和盆腔淋巴结清扫术以及回肠膀胱术,存活至今。1例尿道移行细胞癌行姑息性经尿道后尿道肿瘤电切和前列腺部分电切,术后半年患者死于心肺疾病。结论男性尿道癌以手术治疗为主,辅助化疗和放疗,其预后与肿瘤部位、临床分级和病理分级有关。远端尿道癌预后优于球膜部尿道癌。

Objective To investigate the clinical feature,diagnosis and treatment of carcinoma of male urethral carcinoma.Methods The data of 3 cases of urethral carcinoma of male,diagnosed and treated in our hospital from 2000 to 2008,were summarized and discussed.Results The 3 cases included 2 cases of urethral squamous cancer and 1 case of transitional cell carcinoma.One patient with urethral squamous cancer,who died because of myocardial infarction 2 years after operation,underwent radical cystectomy,prostatovesiculectomy,phallectomy,pubis ablation,pelvic lymphadenectomy and ileum conduit urinary diversion.The other patient underwent the same operation but is still alive.The patient with transitional cell carcinoma was treated with transurethral electrocision of posterior urethral carcinoma and partial resection of prostate,died half a year after operation because of sudden death.Conclusions Surgery is the primary treatment for male patients with urethral carcinoma,while radiotherapy combined with chemotherapy is secondary.Long-term survival is related to tumor position,clinical classification and pathological grade.The prognosis of distal urethral carcinoma is more favorable than that of bulbar and membranous urethral carcinoma.