孤立性纤维性肿瘤研究进展

Solitary fibrous tumors research: a review of the literature

孤立性纤维性肿瘤(solitary fibrous tumors,SFTs)是一种少见的间叶来源性肿瘤,好发于胸腹腔,胸膜外其他组织也可发生,临床多呈良性过程。近年来研究发现良性SFTs可发展为恶性孤立性纤维性肿瘤(malignant solitary fibrous tumors,MSFTs)。在临床病理学上,SFTs需与其他梭形细胞肿瘤鉴别,而及时准确的诊断对SFTs的治疗和预后评估具有重要意义。

Solitary fibrous tumors（SFTs） are a kind of rare mesenchymal origin tumors,frequently occurring in chest and abdominal cavity,but also have been reported in other organizations outside the pleura.Most of SFTs behave benign clinical process,however,recent studies have showed that some benign SFTs can change into malignant solitary fibrous tumors（MSFTs）.In clinical and pathological,SFTs should be differentiated with some spindle-shaped tumors,conquently,accurate pathologic diagnosis of SFTs is of great significance for the treatment and prognosis appraisement of patients.In this paper,recent clinical and pathological study progress on SFTs will be reviewed.