摘要
目的:探讨吸烟对无其他心血管危险因素的年轻勃起功能障碍(ED)患者内皮功能的影响。方法:我院泌尿外科门诊和住院ED患者,其中吸烟组21例,非吸烟组48例,健康对照组16例,所有受试者均进行肱动脉血流介导的内径扩张功能(FMD)的测定,同时检测其血压、血糖、血脂等指标。结果:与健康对照组相比,ED组患者FMD明显降低,而ED组中吸烟组FMD又明显低于非吸烟组[吸烟组(6.0±0.8)%,非吸烟组(9.7±2.5)%,对照组(14.0±2.5)%],组间差异均有统计学意义(P<0.05)。结论:ED患者存在内皮功能障碍,吸烟进一步加重ED患者内皮功能的损害。
Objective： To determine whether smoking affects the endothelial function of young ED patients with no cardiovascular disease.Methods： This study included 69 ED patients（21 smokers and 48 non-smokers） and 16 age-matched normal healthy controls.All underwent measurement of brachial artery flow-mediated vasodilation（FMD） and examinations of blood pressure,cholesterol,triglycerides and glucose.Results： Brachial artery FMD was remarkably decreased in the ED patients,even more significantly in the smokers（[6.0±0.8] %） than in the non-smokers（[9.7±2.5] %）（P0.05）,as compared with that in the normal healthy controls（[14.0±2.5] %,P0.05）.Conclusion： Endothelial function is impaired in ED patients,and is further damaged by smoking.
出处
《中华男科学杂志》
CAS
CSCD
北大核心
2011年第5期414-417,共4页
National Journal of Andrology
基金
广东省科技计划项目(2009B13030801178
2008B080703056)~~
