正常眼共焦扫描激光多普勒视网膜血流图

Confocal scanning laser Doppler retinal flowmetry in normal eyes

目的 探讨共焦扫描激光多普勒视网膜血流图的临床应用价值。方法 应用Ｈｅｉｄｅｌｂｅｒｇ共焦扫描激光多普勒视网膜血流图仪对４８ 例（８２ 只正常眼）视乳头及视网膜血流灌注进行检测。结果 视乳头大血管血流量为２０３１４ ±７４７７，血流速为６ ２７２４３ ±２ ２６００７ ，红细胞移动速率为１３１４ ±２５８ ；视乳头筛板处的血流量为２６３６ ±１４７４ ，血流速为４６７９９ ±２７０１５ ，红细胞移动速率为１９３ ±１０７ 。颞侧视乳头盘沿的血流量为２２９０ ±１１３２，血流速为５１４５３ ±３７０２１，红细胞移动速率为１６９±１１２ ；鼻侧视乳头盘沿的血流量为２１７７ ±９８３，血流速为４９３２１ ±２９０２９，红细胞移动速率为１６５±０９０；颞侧与鼻侧比较差异无显著性（ｔ 值分别为０６８２ ５ ，０４１０ ４，０２５０ １，Ｐ＞ ００５） 。颞侧视乳头旁视网膜的血流量为３２５５ ±１３００，血流速为５５８６３ ±２９３４５ ，红细胞移动速率为１７８ ±０８３；鼻侧视乳头旁视网膜的血流量为２０６１ ±８９２ ，血流速为３５８６４ ±２１２６６ 。

Objective To introduce a new noninvasive equipment to measure the blood flow of optic nerve head and retina Methods The scanning laser Doppler retinal flowmeter (Heidelberg Engineering, Heidelberg, Germany) was used to measure the blood flow of optic nerve head and retina of 82 eyes of 48 normal individuals Results The average blood flow volume, blood flow velocity and the erythrocyte flow velocity of the vessel in optic nerve head were 203 14±74 77, 6 272 43±2 260 07, 13 14±2 58 respectively; they were 26 36±14 74, 467 99±270 15, 1 93±1 07 in lamina cribrosa; 22 90±11 32, 514 53±370 21, 1 69±1 12 in the temporal rim of papilla; 21 77±9 83, 493 21±290 29, 1 65±0 90 in nasal rim of papilla; 32 55±13 00, 558 63±293 45, 1 78±0 83 in the temporal juxtapapillary retina; 20 61±8 92, 358 64±212 66, 1 20±0 66 in the nasal juxtapapillary retina;28 89±11 52, 497 97±278 70, 1 64±0 83 in the avascular area of temporal retina; 25 00±8 04, 455 87±203 65, 1 55±0 64 in the avascular area of nasal retina Conclusions Confocal laser scanning Doppler retinal flowmetry, which is based on confocal laser scanning technology and Doppler flowmetry, is an effective clinical method to determine the blood flow in optic nerve head and retina