双侧脑室穿刺引流与腰穿脑脊液置换治疗重型脑室出血临床观察

Clinical observation on bilateral ventricle drainage and lumbar puncture cerebrospinal fluid replacement in the treatment of severe ventricular hemorrhage

目的探讨双侧脑室穿刺引流与腰穿脑脊液置换治疗重型脑脑室出血的有效性。方法重型脑室出血患者72例,随机分为A、B、C 3组,分别进行内科治疗结合单侧脑室穿刺引流术(A组)、内科治疗结合双侧脑室穿刺引流术(B组)与内科治疗结合双侧脑室穿刺引流术加腰穿脑脊液置换(C组)。结果 C组脑室积血清除时间明显比A、B组缩短(P<0.05),且病死率低。结论双侧脑室穿刺引流加腰穿脑脊液置换治疗重型脑室出血是一种比较安全、有效的方法。

【Objective】 To evaluate the effect of bilateral ventricular drainage and craniospinal fluid replacement on patients with severe ventricular haemorrhage.【Methods】 72 cases with severe ventricular haemorrhage were randomly divided into A,B,C groups.A and B groups received unilateral or bilateral ventricular drainage respectively,and C group received bilateral ventricular drainage and craniospinal fluid replacement.【Results】 Compared with other two groups（A,B）,the duration of intraventiclar hematoma in C group was obviously shorter（P 0.05）,and a lower mortality in group C.【Conclusion】 Bilateral ventricular drainage and craniospinal fluid replacement is an effective and safe treatment for severe ventricular haemorrhage.