运动对兔膝退变关节软骨形态学的影响

The influence of movement on the morphology of the decayed joint cartilage of rabbits

目的：了解不同运动方式对退变关节软骨的形态学影响。方法：以新西兰白兔为研究对象，用伸膝位石膏固定８ 周的方法建立骨关节炎动物模型，按运动方式不同，随机分成５ 组，从光镜、扫描电镜两方面观察运动对退变关节软骨的组织形态学影响。结果：关节制动可诱发关节软骨退变，运动对退变软骨具有保护和促进修复作用。结论：关节适宜运动可促进退变关节软骨的修复和重塑，增加关节稳定性。

Objective:To investigate the influence of different ways of movement upon the morphology of decayed joint cartilage of rabbits.Method:Taking Newzealand rabbits as our study objects, we have build some osteoarthritis(OA) animal models by fixing the rabbits′ left posterior knee joint in stretching state plaster for 8 weeks. According to different ways of movement, the influence of movement upon the morphology of decayed arthrochondritis under light microscopy and scanning electron microscopy were observed. Result: Joint immobilization could evoke arthrochondritis decay, while movement could serve to protect and repair decayed arthrochondritis. Conclusion:Proper degree joint movement of could be helpful to repair and rebuild decayed arthrochondritis, and make it more stable. Author′s address\ No. 150 Central Hospital of the PLA, Luoyang, Henan, 471031