老年患者开胸术前硝酸甘油雾化吸入对氧分压的影响

Efficacy of nebulized nitroglycerin inhalation in the preoperative preparation with thoracotomy of elder patients

目的:观察老年患者开胸手术前硝酸甘油雾化吸入后对氧分压的影响。方法:选择年龄65岁以上拟行开胸手术的老年患者40例,随机分为两组。入院后患者吸氧、抗炎及肺功能锻炼。生理盐水(NS)组以生理盐水雾化吸入,硝酸甘油(Nitro)组以硝酸甘油雾化吸入,吸入前监测BP、HR、ECG和SpO2。分别于入院时、吸入治疗后行血气分析,观察氧分压的变化。结果:两组患者的氧分压均得到不同程度的提高,Nitro组与NS组比较差异有统计学意义(P<0.05)。结论:硝酸甘油雾化吸入可以更好的改善老年患者麻醉前的氧分压。

Objective To observe the influence of the partial pressure of oxygen in the elder patients with nebulized nitroglycerin inhalation before thoracic surgery. Methods 40 patients over 65 years old before thoracic surgery were randomly divided into two groups. anti-inflammation and functional exercise of lung after The patients were treated by routine oxygen inhalation, admission. Furthermore, the controll group inhaled nebulized normal saline and the observed group inhaled nebulized nitroglycerin. The BP, HR, ECG and SpO2 were mornitored during the inhalation. The arterial blood gas analysis was performed and the change of partial pressure of oxygen was observed. Results The partial pressure of oxygen in the two groups were both increased.. There was significant difference between the two groups （P 〈 0.05）. Conclusion Nebulized nitroglycerin inhalation may be better improve the partial pressure of oxygen in the elder patients before anesthesia.