摘要
目的:观察还原型谷胱甘肽联合丹参治疗酒精性肝病的疗效。方法:将50例酒精性肝病患者随机均分为2组,对照组25例,给予门冬氨酸钾镁、甘草酸二铵和维生素C静脉滴注;治疗组在对照组基础上加用谷胱甘肽1200mg和复方丹参注射液20mL,qd,静脉滴注。2组疗程均为1个月。监测治疗前、后肝功能的变化。结果:治疗组在肝功能改善方面明显优于对照组(P<0.05);治疗组和对照组总有效率分别为92.0%和68.0%,2组比较有显著性差异(P<0.05)。结论:还原型谷胱甘肽联合丹参治疗酒精性肝病确有良好疗效。
OBJECTIVE: To observe the clinical efficacy of reduced glutathione combined with Salvia miltiorrhiza for alcoholic liver disease. METHODS: 50 patients with alcoholic liver disease were randomly divided into 2 groups. 25 patients in control group received intravenous infusion of potassium magnessium aspartata and diammonium glycyrrhizinate and vitamin C continuously. Trial group were given reduced glutathione 1 200 mg and S. miltiorrhiza 20 mL once a day. The treatment period of 2 groups lasted for one month. The changes of liver function were monitored before and after treatment. RESULTS: The improvement of liver function in trial group was better than control group significantly(P0.05). Total effective rate of 2 groups were 92.0% and 68.0% respectively. There were significant differences(P0.05). CONCLUSION: Reduced glutathione combined with S. miltiorrhiza for alcoholic liver disease shows satisfactory effect.
出处
《中国药房》
CAS
CSCD
北大核心
2011年第24期2284-2285,共2页
China Pharmacy
关键词
酒精性肝病
还原型谷胱甘肽
丹参
肝功能
Alcoholic liver disease
Reduced glutathione
Salvia miltiorrhiza
liver function