期刊文献+

还原型谷胱甘肽对肝癌肝动脉化疗栓塞后肝脏损害的保护作用 被引量:1

原文传递
导出
摘要 目的探讨还原型谷胱甘肽对肝癌肝动脉化疗栓塞(TACE)后肝脏损害的保护作用及安全性。方法 36例肝癌接受TACE后的患者被随机分为两组,治疗组予还原形谷胱甘肽,对照组给予葡萄糖醛酸内酯。治疗3周后观察患者临床症状、肝功能等的变化。结果治疗组总有效率高于对照组(P<0.05),两组均有TACE术后并发症,治疗组较对照自觉症状改善更明显,两组均无不良反应发生。结论还原型谷胱甘肽对TACE术后肝损害有较好的改善作用及安全性。
作者 殷芳 宁珠
出处 《中国误诊学杂志》 CAS 2011年第16期3828-3829,共2页 Chinese Journal of Misdiagnostics
  • 相关文献

参考文献6

二级参考文献33

  • 1卢永科,川岛明,堀井郁夫,仲来福.顺铂对大鼠肝细胞毒性及谷胱甘肽的保护作用[J].中国公共卫生,2004,20(4):440-441. 被引量:8
  • 2叶新平,黎乐群.Ⅱ相代谢酶基因多态性与肝癌遗传易感性研究进展[J].广西医学,2004,26(11):1656-1658. 被引量:3
  • 3贺菽嘉,覃甲仁,顾永耀,钟卫干,苏上贵.Ⅱ相代谢酶基因多态性与广西肝癌发生的关系[J].实用癌症杂志,2004,19(5):460-462. 被引量:7
  • 4贺菽嘉,顾永耀,廖志红.Ⅱ相代谢酶基因多态性联合烟酒习惯对肝癌易感性的影响[J].基础医学与临床,2007,27(6):666-669. 被引量:4
  • 5Kroncke KD,Fehsel K,Suschek C,et al.Inducible nitric oxide synthase-derived nitric oxide in gene regulation,cell death and cell survival[J].Int Immunopharmacol,2001(8):1407-1412.
  • 6Francesco DI.Efficacy and safety of high dose cisplatin and cyclophosphamide with glutathione protection in the treatment of bulky advance depithelial ovarian cancer[J].Cancer Chemother Pharmalcol,1990,25(5):355-360.
  • 7Paolicchi A,Pompella A,Tonarelli P,et al.Gammaglutamy ltran-speptidase activity in human ovarian carcinoma[J].Anticancer Res,1996,16(5B):3053-3058.
  • 8Schmidinger M,Budinsky AC,Wenzel C,et al.Glutathione in the prevention of cisplatin induced toxicities.A prospectively randomized pilot trial in patients with head and neck cancer and non small cell lung cancer[J].Wien Klin Wochenschr,2000,112(14):617-623.
  • 9Zicca A, Cafaggi S, Mariggio MA,et al. Reduction of cisplatin hepatotoxicity by procainamide hydrochloride in rats[J].Eur J Pharmaco1,2002 ;442 (3) :265-72.
  • 10Hengartner MO. The biochemistry of apoptosis [J]. Nature, 2000 ; 407 (6805) :770-7.

共引文献623

同被引文献17

  • 1王海山,柴宁.丙种球蛋白在儿科临床的应用[J].辽宁中医杂志,2010,37(S1):187-190. 被引量:4
  • 2陈力,刘砚韬,尹如铁,张伶俐.肿瘤化疗患者并发败血症的诊治进展[J].中国医院用药评价与分析,2007,7(5):339-341. 被引量:1
  • 3Kaneko M,Tsuchido Y,Mugishima H. Intensified chemotherapy increases the survival rats in patients with stage 4 neuroblastoma with Nmyc amplication[J].J Pediatr Hematal Oncol,2002,(08):613-621.
  • 4郭青龙.肿瘤药理学[M]北京:化学工业出版社,2007136.
  • 5Song LQ,Zhang YB,He JJ. The side effects of docetaxel with cyclophosphamide as postoperative adjuvant chemotherapy for elderly breast cancer patients[J].Chinese-German Journal of Clinical Oncology,2011,(07):391-393.doi:10.1007/s10330-011-0815-6.
  • 6Kragg I,Bajorek B,Bagia M. Evaluation of three methods used in the prophylaxis of cyelophosphamide induced hemorrhagic cystitis in bone marrow transplant patients[J].Journal of Oncology Pharmacy Practice:Official Publication of The International Society of Oncology Pharmacy Practitioners,1997,(03):193-199.
  • 7Lyman GH. Guidelines of the national comprehensive cancer network on the use of myeloid growth factors with cancer chemotherapy:a review of the evidence[J].J Natl Compr Canc Netw,2005,(04):557-571.
  • 8Cubeddu LX. Serotonin mechanisms in chemotherapy-induced emesis in cancer patients[J].Oncology(Basel),1996,(01):18-25.
  • 9Warr DG,Hesketh PJ,Gralla RJ. Efficacy and tolerability of aprepitant for the prevention of chemotherapy-induced nausea and vomiting in patients with breast cancer after moderately emetogenic chemotherapy[J].Journal of Clinical Oncology,2005,(12):2822-2830.
  • 10叶凤珍,潘珊.侵蚀性葡萄胎并肺转移化疗后骨髓抑制合并败血症的护理[J].现代医药卫生,2010,26(12):1897-1898. 被引量:1

引证文献1

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部