多重线性回归分析及优选义齿粘附剂配方

Optimization of denture adhesive's formula by multiple linear regression and orthogonal design methods

目的:优选Comfort-DA II型义齿粘附剂配方。方法:以粘结抗张强度值为评价标准,联用多重线性回归分析及正交设计法确定Comfort-DA II型义齿粘附剂的最佳配比。结果:聚氧化乙烯0.3125g、甲基纤维素1.250g、海藻酸钠0.5625g、羟乙基纤维素0.154g时,义齿粘附剂的粘结抗张强度值最高。结论:联用多重线性回归分析及正交设计法可有效地确定Comfort-DA II型义齿粘附剂的最佳配比。

Objective： Optimization of Comfort-DA II＇ s formula. Methods： Each factor of affecting tensile bond strength of Comfort-DA II was analyzed to select the best formula by combining multiple linear regression and orthogonal design. Results： When polyethylene oxide is 0.3125g, methyl cellulose is 1.250g, sodium alginate is 0.5625g, and hydroxyethyl cellulose is 0.154g, tensile bond strength of Comfort-DA II is at the best condition. Conclusion： The combination of multiple linear regression and orthogonal design is an effective methodology in the optimization of Comfort-DA II＇s formula.