常州地区妇女HPV感染状况调查

An Survey of Human Papilloma Virus Infection Situation of Women in Changzhou

目的:研究常州地区普通妇女人群中HPV感染状况,为宫颈癌的预防及治疗提供理论依据。方法:采用PCR与基因芯片技术,对常州地区参加妇科体检的744名妇女进行HPV分型检查,并对不同分型感染情况进行统计学分析。结果:744名妇女中共检出HPV阳性者157例,感染率为21.10%。在高危型HPV感染妇女中,共计83.64%的妇女感染了以下六种亚型,依次是16型46例,58型28例,33型24例,18型18例,31型11例以及52型11例。结论:鉴于高危型HPV与宫颈癌发生的密切关系,对普通妇女人群展开HPV检测具有预防与治疗意义。

To investigate HPV （human papilloma virus） of women in Changzhou for providing theoretical basis of prevention and treatment on the cancer of uterine cervix. Methods： A total of 744 women with HPV in Changzhou were examined by PCR and gene chip technique. Results： Of 744 cases, 157 cases （21.10%） were HPV positive. And of the high risk type HPV, HPV-16, 58, 33, 18, 31 and 52 were the highest infection rate subgroups. Conclusion： There was relationship between the high risk type HPV and incidence of cancer of uterine cervix, it was important to detect the HPV infection for prevention and treatment on the cancer of uterine cervix.