神经梅毒5例临床分析

Clinical Analysis of 5 Cases with Neurosyphilis

目的:探讨梅毒感染后致神经系统损害的临床特征,加强对神经梅毒的认识。方法:回顾性分析5例神经梅毒患者的临床特点、血清学变化、影像学资料。结果:5例梅毒血清学检查、脑脊液梅毒检查均阳性,5例头核磁检查存在特异性改变(4例冠状位可见海马异常信号),临床特征缺乏特异性。结论:神经梅毒好发于中年男性,梅毒全身症状可不明显,其临床表现多样,容易误诊和漏诊,临床应重视对患者临床特征识别,尤其对患者脑脊液及影像学检查结果识别,对神经梅毒患者的诊治有重要的现实意义。

To investigate the syphilis infection damages the nervous system caused by the clinical features, enhance the understanding of neurosyphilis. Methods： A total of 5 patients with neurosyphilis were selected. Their clinical features, serological changes, image data were retrospectively analysed Results： 5 cases of syphilis serologic test, cerebrospinal fluid syphilis check all positive, 5 cases head rnri inspection exist specific change （4 cases of coronal visible hippocarnpal anomalous signals）, clinical features lack of specificity. Conclusions： Neurosyphilis occurs in middle-aged men; syphilis,systemic symptoms may be obvious, its various clinical manifestations, misdiagnosis and missed diagnosis,clinical recognition of the clinical characteristics of patients with special emphasis on eerebrospinal fluid and imaging results to identify, for patients with neurosyphilis diagnosis has important practical significance.