摘要
目的:研究南方某部反流性食管炎(RE)的患病情况及其与幽门螺杆菌(Hp)的关系。方法:我们的前期问卷调查研究结果显示GERD军人102例,根据入选标准有91例GERD患者入选,其中低分组(12-15分)47例、中分组(16-20分)34例、高分组(〉20分)10例。另随机抽取60例非GERD军人为对照组。共151例军人接受胃镜检查,同时采用14C-尿素呼气试验与取胃窦小弯粘膜行组织快速尿素酶试验两种方法检测Hp,两种方法结果均阳性者判为Hp阳性。结果:GERD组与对照组RE检出率分别为42.86%(39/91)、3.33%(2/60),差异显著(P〈0.05);但GERD各积分组之间RE检出率无显著差异(P〉0.05)。GERD组中39例RE,其中A、B级分别22例、13例(共占89.74%),C、D级分别3例、1例(共占10.26%);另检出8例BE(8/91,8.79%),均为岛型、舌型或混合型。症状积分与RE分级情况线性回归R值为0.276(P〉0.05),症状积分与RE级别之间无明显线性关系。RE组Hp感染率为58.97%(23/39),略低于对照组(P〉0.05)。结论:军人RE检出率及Hp感染率均不低,RE检出率与Hp感染无明显关联。
Objective:To assess the clinic characteristic of reflux esophagitis(RE) in Southern Chinese military personnel and the relationship between RE incidence and Helicobacter pylori(Hp).Method:91 qualified GERD patients were selected.47 patients were in lower score group(Sc=12~15).34 patients were in moderate score group(Sc=16~20).10 patients were in high score group(Sc20).60 cases were took in control group(Sc12)with stratified random sampling method.All of the 151 cases accepted gastroscopy and Hp detection with the method of 14CUBT and RUT.Results:The prevalence of RE in GERD group(42.86%,39/91) was significantly higher than that in control group(3.33%,2/60)(P0.05).But the difference among GERD integrations was not statistically significant(P0.05).There were 22 cases in grade A,13 cases in grade B,3 cases in grade C and 1 case in grade D.89.7% of RE patients were in low grade(grade A and grade B).Eight GERD patients suffered from Barrett's esophagus.Neither esophageal stricture nor esophageal adenocarcinoma was detectived.No significant correlation was shown between the degrees of RE and GERD scores(R=0.276,P0.05).The infection rate of Hp in RE group(58.97%,23/39) is a litter lower than that in control group(61.67%,37/60),(P0.05).Conclusion:The prevalence of RE and the infection rate of Hp in Southern Chinese military personnel are high.No impact of Hp on the severity of RE is shown.
出处
《福州总医院学报》
2011年第2期82-84,108,共4页
Journal of Fuzhou General Hospital