摘要
随着社会经济的发展、生活方式的改变,肥胖人群日益增多,脂肪肝的发病率也呈攀升趋势,且酒精性脂肪肝病并非独占鳌头,另一类脂肪性肝病逐渐走入了人们的视线——非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD),
出处
《福州总医院学报》
2011年第2期97-99,共3页
Journal of Fuzhou General Hospital
二级参考文献77
-
1[9]Uesugi T, Froh M, Arteel GE, Bradford BU, Wheeler MD, Gabele E, Isayama F, Thurman RG. Role of lipopolysaccharidebinding protein in early alcohol-induced liver injury in mice. J Immunol2002; 168:2963-2969
-
2[10]Faggioni R, Fantuzzi G, Gabay C, Moser A, Dinarello CA, Feingold KR, Grunfeld C. Leptin deficiency enhances sensitivity to endotoxin-induced lethality. Am J Physiol 1999; 276: R136-R142
-
3[11]Li Z, Yang S, Lin H, Huang J, Watkins PA, Moser AB, Desimone C, Song XY, Diehl AM. Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease. Hepatology 2003; 37:343-350
-
4[12]Hug H, Strand S, Grambihler A, Galle J, Hack V, Stremmel W,Krammer PH, Galle PR. Reactive oxygen intermediates are involved in the induction of CD95 ligand mRNA expression by cytostatic drugs in hepatoma cells. J Biol Chem 1997; 272:28191-28193
-
5[13]Feldstein AE, Canbay A, Angulo P, Taniai M, Burgart LJ, Lindor KD, Gores GJ. Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis.Gastroenterology 2003; 125:437-443
-
6[14]American Gastroenterological Association medical position statement: nonalcoholic fatty liver disease. Gastroenterology 2002; 123:1702-1704
-
7[15]Andersen T, Gluud C, Franzmann MB, Christoffersen P. Hepatic effects of dietary weight loss in morbidly obese subjects.J Hepatol1991; 12:224-229
-
8[16]Luyckx FH, Scheen AJ, Desaive C, Dewe W, Gielen JE, Lefebvre PJ. Effects of gastroplasty on body weight and related biological abnormalities in morbid obesity. Diabetes Metab 1998;24:355-361
-
9[17]Drenick EJ, Simmons F, Murphy JF. Effect on hepatic morphology of treatment of obesity by fasting, reducing diets and small-bowel bypass. N Engl J Med 1970; 282:829-834
-
10[18]Cox KL, Burke V, Morton AR, Beilin LJ, Puddey IB. Independent and additive effects of energy restriction and exercise on glucose and insulin concentrations in sedentary overweight men. Am J Clin Nutr 2004; 80:308-316
共引文献15
-
1张晓兰,张志钢,海春旭,王旭霞,冯国华,刘美媛,闻勤生.网络抗氧化剂对大鼠非酒精性脂肪肝炎模型疗效的动态观察[J].现代生物医学进展,2008,8(2):213-218. 被引量:2
-
2王慧超,叶红军,韦始亮,刘晓翌,万汇涓,杜意平.复方甘草甜素脂质体干预大鼠非酒精性脂肪性肝炎的疗效观察[J].临床肝胆病杂志,2008,24(3):199-201. 被引量:2
-
3郭斯敏,谢青.非酒精性脂肪性肝病的无创性诊断方法及检测系统的研究进展[J].实用肝脏病杂志,2008,11(4):279-284. 被引量:3
-
4林刚,钟妍,范建高.2型糖尿病对非酒精性脂肪性肝病的影响[J].国际消化病杂志,2008,28(6):455-457. 被引量:3
-
5叶红军,韦始亮,王慧超,刘晓翌,万汇涓,易学瑞,袁有成,孔祥平.复方甘草甜素脂质体防治大鼠脂肪肝性肝纤维化[J].中华肝脏病杂志,2009,17(11):877-878. 被引量:3
-
6詹莉,张丹,敖英,吴勇,汪晖.小檗碱对高脂饲料所致大鼠非酒精性脂肪肝的保护作用[J].武汉大学学报(医学版),2010,31(1):65-67. 被引量:4
-
7魏来,赵春景.番茄红素对大鼠非酒精性脂肪肝的作用研究[J].中国药业,2010,19(3):3-5. 被引量:9
-
8吴志军,金烨,廖为民.非酒精性脂肪肝治疗概况[J].中国医学创新,2010,7(5):183-184. 被引量:4
-
9李琪波.异甘草酸镁联合腺苷蛋氨酸治疗胆汁淤积性肝炎30例分析[J].中国医师进修杂志,2010,33(7):58-59. 被引量:4
-
10杨莉丽,叶红军,王慧超,刘晓翌,万汇涓,邹兵.丹参对大鼠非酒精性脂肪性肝炎和脂质代谢的作用[J].现代消化及介入诊疗,2010,15(3):144-146. 被引量:6
同被引文献33
-
1周红宇,阳学风.瘦素对肝细胞三酰甘油沉积的影响[J].临床军医杂志,2006,34(3):265-268. 被引量:7
-
2橋本悦子,谷仁烨.非酒精性脂肪性肝炎的诊断标准[J].日本医学介绍,2007,28(4):146-148. 被引量:5
-
3季宇彬,张宇金,何立巍.甜菜碱对S_(180)荷瘤小鼠血清5种肿瘤标志物的影响[J].中国药学杂志,2007,42(16):1221-1224. 被引量:3
-
4Berzsenyi MD, Roberts SK, Preiss S, et al. Hepatic TLR2 & TLR4 expression correlates with hepatic inflammation and TNF-a in HCV & HCV/HIV infection [J]. Journal of Viral Hepatitis, 2011,18 : 852-860.
-
5Day CP, James OF. Steatohepatitis : a tale or two" hit" 9. [ J ]. Gastroenterology, 1998,114 (4) : 842-845.
-
6Alisi D, Panera N. Toll-like receptor 4 : a starting point for proinflammatory signals in fatty liver disease [ J ]. Hepatolo- gy,2010,51 (2) :714-715.
-
7Mencin A, Kluwe J, Schwabe RF. Toll-like receptors as targets in chronic liver diseases [ J]. Gut, 2009,58 (5) : 704 -720.
-
8Csak T, Velayudham A, Hritz I, et al. Deficiency in mye- loid differentiation factor-2 and toll-like receptor 4 expres- sion attenuates nonalcoholic steatohepatitis and fibrosis in mice [ J]. Gastrointestinal and liver Physiolosy ,2011,300 : 433-441.
-
9Singh R, Bullard J, Kalra M,et al. Status of bacterial col- onization, Toll-like receptor expression and nuclear factor- kappa B activation in normal and diseased human livers [ J ]. Clinical Immunology, 2011,138:41-49.
-
10Cusi K. Role of obesity and lipotoxicity in the development of non- alcoholic steatohepatitis(Nash):thophysiology and clinical impli- cations[J].Gastroenteology, 2012,142 ( 4 ) : 711-725.
引证文献3
-
1杨钦河,黄进,张玉佩,王强,何秀敏,冯高飞,王文晶,李哲华.疏肝健脾方药对NASH大鼠肝组织TLR4 mRNA及其蛋白表达的影响[J].中药材,2013,36(1):78-84. 被引量:8
-
2沈炜.甜菜碱对非酒精性脂肪肝大鼠瘦素影响的研究[J].浙江临床医学,2014,16(6):862-863.
-
3王申.瑞舒伐他汀对非酒精性脂肪性肝炎患者血清TNF-α、IL-6和hs-CRP浓度的影响[J].中国现代医药杂志,2015,17(12):31-34. 被引量:4
二级引证文献12
-
1税嘉诚,胡财愿,刘奕均,金幸,王诗白,孙建鑫,付航,廖国澳,梁荫基,闫海震,杨钦河.参苓白术散的实验研究进展[J].医学信息(医学与计算机应用),2014,0(30):335-336.
-
2刘芬,刘艳菊,田春漫.苍术提取物对实验性脾虚证大鼠胃肠动力及免疫功能的影响[J].吉林大学学报(医学版),2015,41(2):255-260. 被引量:22
-
3刘芬,刘艳菊,田春漫.苍术提取物对脾虚证大鼠胃粘膜及胃肠免疫功能的影响[J].南方医科大学学报,2015,35(3):343-347. 被引量:29
-
4王斌,李敏,侯建平.基于TLR4-NFκB信号通路的柴胡-黄芩药对抗肝纤维研究[J].中药药理与临床,2015,31(3):103-106. 被引量:11
-
5阳长明,王建新.论中药复方制剂质量源于设计[J].中国医药工业杂志,2016,47(9):1211-1215. 被引量:36
-
6邓远军,张玉佩,杨钦河,何毅芳,梁荫基,韩莉,梁曙.柴胡疏肝散对非酒精性脂肪性肝病大鼠肝组织SIRT1/p53通路相关蛋白的影响[J].中药新药与临床药理,2016,27(5):597-601. 被引量:8
-
7农汝楠,王竟静,吴燕春,刘舒凌,刘偲翔,周至品.基于TLR4信号通路的中药抗肝脏疾病作用研究进展[J].中国实验方剂学杂志,2019,25(16):201-212. 被引量:19
-
8邓恺伦.疏肝降脂汤治疗肝郁脾虚型非酒精性脂肪肝44例[J].西部中医药,2020,33(4):96-99. 被引量:10
-
9吴新国,石永强,赵向阳,王小平.小檗碱联合瑞舒伐他汀治疗非酒精性脂肪性肝病的临床疗效[J].医学综述,2020,26(14):2905-2909. 被引量:7
-
10方晓慧,王彩娥,邓娇,祁兴顺.他汀类药物治疗脂肪性肝病的研究进展[J].世界华人消化杂志,2023,31(16):659-665. 被引量:1
-
1王静,王中丽,夏冰.非酒精性脂肪肝合并高血压与胰岛素抵抗的关系[J].医学新知,2011,21(1):37-38. 被引量:1
-
2田庚善.脂肪肝,也可与酒精无关[J].家庭医药(就医选药),2013(6):25-25.
-
3郭伟,高明松,叶正华,李阳,涂嘉骏,雷维民.二甲双胍对2型糖尿病合并非酒精性脂肪肝病患者血清nesfatin-1及肝脂肪变的影响[J].疑难病杂志,2014,13(4):374-377. 被引量:10
-
4张月华,陈伟良.糖尿病的肝脏并发症—非酒精性脂肪肝病[J].现代医药卫生,2006,22(19):2961-2962.
-
5卢丙艳,谢云.胰岛素抵抗与2型糖尿病合并非酒精性脂肪肝相关性研究[J].辽宁医学杂志,2017,31(1):3-5. 被引量:3
-
6胡卫,汤绍辉.非酒精性脂肪肝病与高尿酸血症的相关性分析[J].临床内科杂志,2013,30(10):690-691. 被引量:4
-
7酒精性脂肪肝一定要戒酒吗[J].中国家庭医生,2013(3):39-39.
-
8王亚平,杨悦亚,陈理书,张志银,要全保,庄敏之,胡南华,朱艳,郑昕,周菲,张迪,郭兆玮.加味降脂理肝汤治疗痰瘀质非酒精性脂肪肝病63例[J].上海中医药杂志,2008,42(6):23-25. 被引量:9
-
9王洋,李燚.102例脂肪肝病因分析及防治[J].齐齐哈尔医学院学报,2013,34(4):513-513. 被引量:4
-
10翟厚峰,姚茜,吕欣,金慧敏,陈婷.酒精性脂肪肝病患者颈动脉内膜中层厚度增加的影响因素分析[J].中国医药指南,2016,14(33):23-23.